Protein Alignment Spn28Da and Serpina12

DIOPT Version :10

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_620180.2
• Gene: Serpina12 / 191570
• RGDID: 708485
• Length: 414
• Species: Rattus norvegicus
• Alignment Length: 376
• Identity: 94/376 - (25%)
• Similarity: 183/376 - (48%)
• Gaps: 31/376 - (8%)

  Fly    16 QFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPE-DKKNVATIYDK 79
            :|..:|.:....:::|.||..|||.:....||:.:||..:|..|:|...|..| ..:::...:..
  Rat    54 EFGFKLLQRLASNSRQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSDRDMHMGFHY 118

  Fly    80 LLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVLD 144
            ||.||.|..:...:.:.|.||:::.:...:|:.||....:.|:.......|.......||.::..
  Rat   119 LLQKLNRETQDVKMSIGNALFMDQRLRPQQRFLKLAKNLYDADMILTNFQDLENTQKNINKYISR 183

  Fly   145 QTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGR 209
            :|.:.:::::  .::.|....::.|..:|:|.|:..||...||.:.|::.:...|.|.||.|.|.
  Rat   184 KTHNRIENMV--KNIDPGTVMLLTNYIYFQGRWQYEFDPKQTKEEDFFIEEGKTVKVPMMFQRGM 246

  Fly   210 FKMR--TSTIDQIIELPFAYSNLSMVIVLPKDNGSLTQAE----ATIESYPQIVLTEMDVHVQLP 268
            :.|.  :.....|:|:|:. .|::...||| |:|.|...|    |.|.:..:.:|::..|.|.:|
  Rat   247 YDMAYDSQLSCTILEMPYR-RNITATFVLP-DSGKLRLLEQGLQADIFAKWKSLLSKRVVDVWVP 309

  Fly   269 KFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVHKAFIEIDEEG--GSAGSAS- 330
            :..|.....:.:.|..:||..:|....|::.:.:....::.:.||||.:.::|:|  |:|||.:
  Rat   310 RLHISATYNMKKVLSRLGISKIFEEHGDLTRISSHRSLKVGEAVHKAELRMNEKGTEGAAGSGAQ 374

  Fly   331 ----ASPIRGLSDYATSVVTFTVNSPFVFMIRDD--DNIYFRGRVVDPLKK 375
                .:|.|           ..:|:||:.||.::  .::.|..|:.:|.:|
  Rat   375 TLPMETPRR-----------MKLNAPFLMMIYENLMPSMIFLARIYNPSEK 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	serpin42Dd-like_insects	12..372	CDD:381070	92/371 (25%)
Serpina12	NP_620180.2	serpinA12_vaspin	40..411	CDD:381026	92/371 (25%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		5/17 (29%)