DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and Serpina3c

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_011242304.1	Gene:	Serpina3c / 16625	MGIID:	102848	Length:	436	Species:	Mus musculus

Alignment Length:	385	Identity:	110/385 - (28%)
Similarity:	177/385 - (45%)	Gaps:	35/385 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVTTSVLGQFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKN 72
            |...|:...|...||:.....|...||:.|||.:...::::.:||.|||..|:...||....:..
Mouse    64 LTLASINTDFAFSLYKKLALKNPDTNIVFSPLSISAALAIVSLGAKGNTLEEILEGLNFNLTETP 128

  Fly    73 VATI---YDKLLTKLER-GKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLK 133
            .|.|   :..||.:|.. |::|.| ...:.|||.:.:.:...:.:.....::|||........|:
Mouse   129 EADIHQGFGHLLQRLSHPGEQVQI-STGSALFVEKHLQILAEFQEKARALYQAEAFTADFQQPLE 192

  Fly   134 AAWAINDWVLDQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQ 198
            |...|||:|.:||...:|.:|  |||..|...|::|..:|||.||..|:..:|....||:.....
Mouse   193 ATKLINDYVSNQTQRKIKGLI--SDLDTDTLMVLVNYIYFKGKWKMPFNPRDTFESEFYLDVKRS 255

  Fly   199 VNVNMMSQVGRFKMRTSTI----DQ-----IIELPFAYSNLSMVIVLPKDNGSLTQAEA-----T 249
            |.|.||      |::|.|.    |:     ::||.:. .|.|.:.:|| |.|.:.|.||     |
Mouse   256 VKVPMM------KIKTLTTPYFRDEELSCTVVELKYK-GNASALFILP-DQGRMQQVEASLQPET 312

  Fly   250 IESYPQIVLTEMDVHVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVHK 314
            :..:...:.......:.||||.|.....|...|..:||:::|:..:|:|.:.......:||:|||
Mouse   313 LRKWKNSLRPRKMGELYLPKFSISTDYSLKNILPELGIKEIFSKQADLSGITGTKDLIVSQMVHK 377

  Fly   315 AFIEIDEEGGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMIRDDD--NIYFRGRVVDP 372
            |.:::.|.|....:|:....|.|| ..||:   ..|..|:.:|...|  ...|..::..|
Mouse   378 AVLDVAETGTEGVAATGVNFRILS-RRTSL---WFNRTFLMVISHTDVQTTLFIAKITHP 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	107/372 (29%)
Serpina3c	XP_011242304.1	serpinA3_A1AC	56..434	CDD:381019	110/385 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100