Protein Alignment Spn28Da and Serpinh1

DIOPT Version :10

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_033955.2
• Gene: Serpinh1 / 12406
• MGIID: 88283
• Length: 417
• Species: Mus musculus
• Alignment Length: 364
• Identity: 90/364 - (24%)
• Similarity: 172/364 - (47%)
• Gaps: 20/364 - (5%)

  Fly    21 LYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDK-KNVATIYDKLLTKL 84
            ||::..:|....||:.|||.|...:.::.:|....||::.:..|:..:.: :.|.|...:||..|
Mouse    53 LYQAMAKDQAVENILLSPLVVASSLGLVSLGGKATTASQAKAVLSAEKLRDEEVHTGLGELLRSL 117

  Fly    85 ERG-KKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVLDQTLD 148
            ... .:.....|.:||:...::.....:.:...:|:..|...|...|:..|..:||:|. .||.|
Mouse   118 SNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWA-SQTTD 181

  Fly   149 NVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGRFKMR 213
            . |...:..|:...:.|:::||.|||.:|..:|.......:.|.|::||.|.|.||.:.|.:...
Mouse   182 G-KLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYY 245

  Fly   214 TSTID--QIIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQI-----VLTEMDVHVQLPKFK 271
            ....:  |::|:|.|:...|::|::|.....|.:.|..: :..|:     .:.:..|.:.|||..
Mouse   246 DDEKEKLQMVEMPLAHKLSSLIILMPHHVEPLERLEKLL-TKEQLKAWMGKMQKKAVAISLPKGV 309

  Fly   272 IDFRMELVETLKSMGIQDLFN-SSSDISVLLNQSGTRISQVVHKAFIEIDEEGGSAGSASASPIR 335
            ::...:|.:.|..:|:.:..: :.:|:|.:..:....::.|.|....|.|.|    |:.....|.
Mouse   310 VEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFEWDTE----GNPFDQDIY 370

  Fly   336 GLSDYATSVVTFTVNSPFVFMIRDDD--NIYFRGRVVDP 372
            |..: ..|...|..:.||:|::||:.  ::.|.||:|.|
Mouse   371 GREE-LRSPKLFYADHPFIFLVRDNQSGSLLFIGRLVRP 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	serpin42Dd-like_insects	12..372	CDD:381070	89/362 (25%)
Serpinh1	NP_033955.2	serpinH1_CBP1	35..416	CDD:381003	90/364 (25%)
		Prevents secretion from ER. /evidence=ECO:0000305	414..417