Protein Alignment Spn28Da and SERPINA3

DIOPT Version :9

• Sequence 1: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_001076.2
• Gene: SERPINA3 / 12
• HGNCID: 16
• Length: 423
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 110/377 - (29%)
• Similarity: 173/377 - (45%)
• Gaps: 33/377 - (8%)

  Fly    17 FTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTAL--NLPE-DKKNVATIYD 78
            |...||:..:......|:|.|||.:...::.:.:||...|..|:...|  ||.| .:..:...:.
Human    56 FAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQ 120

  Fly    79 KLLTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWAINDWVL 143
            .||..|.:......|.:.|.:||.|.:.:..|:.:...:.:.:||.|....|...|...|||:|.
Human   121 HLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVK 185

  Fly   144 DQTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVG 208
            :.|...:.|:|  .||......|::|..|||..|:..||..:|....||:||...|.|.|||
Human   186 NGTRGKITDLI--KDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS--- 245

  Fly   209 RFKMRTSTI----DQ-----IIELPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQIVLTEMDV- 263
               :...||    |:     ::||.:. .|.|.:.:|| |...:.:.||.:  .|:.:....|.
Human   246 ---LHHLTIPYFRDEELSCTVVELKYT-GNASALFILP-DQDKMEEVEAML--LPETLKRWRDSL 303

  Fly   264 ------HVQLPKFKIDFRMELVETLKSMGIQDLFNSSSDISVLLNQSGTRISQVVHKAFIEIDEE 322
                  .:.||||.|.....|.:.|..:||::.|.|.:|:|.:.......:|||||||.:::.||
Human   304 EFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEE 368

  Fly   323 GGSAGSASASPIRGLSDYATSVVTFTVNSPFVFMI--RDDDNIYFRGRVVDP 372
            |..|.:|:|..|..||....:......|.||:.:|  .|..||:|..:|.:|
Human   369 GTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	108/372 (29%)
SERPINA3	NP_001076.2	serpinA3_A1AC	40..421	CDD:381019	110/377 (29%)
		RCL	369..394		7/24 (29%)
		O-glycosylated at one site	381..389		2/7 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010