DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Da and serpinb10

DIOPT Version :9

Sequence 1:	NP_001036345.1	Gene:	Spn28Da / 34082	FlyBaseID:	FBgn0051902	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_031760330.1	Gene:	serpinb10 / 100497689	XenbaseID:	XB-GENE-5769609	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	373	Identity:	99/373 - (26%)
Similarity:	187/373 - (50%)	Gaps:	23/373 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QFTKQLYRSFLQDNKQYNIIASPLCVEIGMSMILMGADGNTANELRTALNLPEDKKNVATIYDKL 80
            :||..:.|...:.....|::.|.:.:.|.::|:.:||.||||.::..||:. ::.::|...:..|
Frog     9 EFTIDVLREISKTAAGQNVVFSSMSIMISLAMVYLGAHGNTAADMGKALHF-DEVEDVHAQFRVL 72

  Fly    81 LTKLERGKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKLADRLKAAWA-INDWVLD 144
            |.:|.:......|...|:||..:.......:.|.:|..:.|..|.:..:...:|..: ||.|:.:
Frog    73 LKELMKNGNDYTLTTVNKLFGEKKYYFLPTFLKAINAFYGAPLEKVDFSSNPEATRSYINAWIQE 137

  Fly   145 QTLDNVKDIIIPSDLTPDESAVMINAAFFKGYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGR 209
            :|...:::::..:.::|:...::.|..:|...|.|:|.:..|....|.:..:.|:.||||:.:..
Frog   138 KTKGKIQNLLPENSISPNTVLMVANTLYFLANWTTQFSEHATSKAPFTLITNEQIKVNMMATMNT 202

  Fly   210 FKMR--TSTIDQIIELPFA-YSNLSMVIVLPKDNGSLTQAEATIESYPQIV-------LTEMDVH 264
            |.|:  .:....::|||:. ..:|||||:||.::..||:.:..| ||..:.       ::...:.
Frog   203 FNMKRIKNPGMSVLELPYGDTKDLSMVIMLPDNSTVLTKVDREI-SYENLSKWTRSENMSSNYLA 266

  Fly   265 VQLPKFKIDFRMELVETLKSMGIQDLFNSS-SDISVLLNQSGTRISQVVHKAFIEIDEEGGSAGS 328
            |.||:|:::....|.:.|.|:|:...|:.| ::.|.:..|....:|.|.||.|||::|:|..|.|
Frog   267 VYLPRFRMEKSFSLKKVLSSLGMSSAFSQSRANFSGMGKQKQLYVSDVHHKTFIEVNEKGTEAAS 331

  Fly   329 ASAS--PIRGLSDYATSVVTFTVNSPFVFMIRDDDN--IYFRGRVVDP 372
            |:.|  .||.|::     ..|..:.||.|.||.:..  |...|:...|
Frog   332 ATGSVMSIRSLAN-----EEFKADRPFHFFIRHNKTNCILLYGKFYSP 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	98/368 (27%)
serpinb10	XP_031760330.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010