Protein Alignment CG7102 and KLHL11

DIOPT Version :10

• Sequence 1: NP_787994.1
• Gene: CG7102 / 34079
• FlyBaseID: FBgn0031961
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_060613.1
• Gene: KLHL11 / 55175
• HGNCID: 19008
• Length: 708
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 85/419 - (20%)
• Similarity: 140/419 - (33%)
• Gaps: 125/419 - (29%)

  Fly    27 GRDERIYAHRLMLMARCKSFKTAKRGEVCRIPGCTVS----PAAPGASTPTTIRLPHVNPELFRQ 87
            ||:.|  |||.:|.|..:.|.....|:........|.    .:.||.           .|:....
Human   105 GREFR--AHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGP-----------EPDTVEA 156

  Fly    88 FILYVYTAKLVLQDSQVFQMMILAQDIGVVELRTACEDHVISTLSVDNACTFLTAVMDIHEKAGA 152
            .|.|:||.::.:....|.:::.||....::.|:..|.:.:...|.:.|.       :.||..|..
Human   157 VIEYMYTGRIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNC-------VAIHSLAHM 214

  Fly   153 KCAASFMERCIIYIGENANECVKTNAFLTLTKDAIIKIISSDYFCLEEEEV-WRCVLSWAKYQAG 216
            ...:....:....|..|.::.::...|.||....|...:|.....::.||| :..||.|.:..|
Human   215 YTLSQLALKAADMIRRNFHKVIQDEEFYTLPFHLIRDWLSDLEITVDSEEVLFETVLKWVQRNA- 278

  Fly   217 VTQPTAHWTEEERARVCQHLSGVM-----------GHVR--LLLIDSQV----FAEEVE------ 258
                      |||.|..:.|..::           .||:  .|:.:::|    .|:.||
Human   279 ----------EERERYFEELFKLLRLSQMKPTYLTRHVKPERLVANNEVCVKLVADAVERHALRA 333

  Fly   259 ----------PTGAVPMELSLERY-----------------RYAALHANKMMDNDKRLQ-PRL-- 293
                      ||..|.:   |.||                 .|.:......:|.|:.:. |.:
Human   334 ENIQSGTCQHPTSHVSL---LPRYGQNMDVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHN 395

  Fly   294 -----AVAV---------NMFPG-SQILKNDNLALQTVLNNWVGVGKQSWRLVFRASTHGYDSGA 343
                 ||||         :|.|| ::.::..|..|.|            |..|....|..:..|.
Human   396 HLDGHAVAVTESYVYVAGSMEPGFAKTVERYNPNLNT------------WEHVCSLMTRKHSFGL 448

  Fly   344 FHRYCDGVAPCMVIGLGSHGEISGGYTDV 372
            ..      ....:..:|.||..|.|:.||
Human   449 TE------VKGKLYSIGGHGNFSPGFKDV 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7102	NP_787994.1	BTB_POZ_ZBTB_KLHL-like	20..112	CDD:349497	20/88 (23%)
		BACK	143..255	CDD:197943	26/129 (20%)
		TLDc	303..477	CDD:214733	14/70 (20%)
KLHL11	NP_060613.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	47..70
		BTB_POZ_KLHL11	71..205	CDD:349550	24/112 (21%)
		PHA03098	90..553	CDD:222983	85/419 (20%)
		BACK_KLHL11	200..287	CDD:350526	23/104 (22%)
		Kelch 1	360..407		8/46 (17%)
		KELCH repeat	399..439	CDD:276965	12/51 (24%)
		Kelch 2	408..453		10/62 (16%)
		KELCH repeat	443..488	CDD:276965	8/35 (23%)
		Kelch 3	455..501		7/17 (41%)
		KELCH repeat	491..541	CDD:276965
		Kelch 4	503..556
		KELCH repeat	567..649	CDD:276965
		Kelch 5	610..661
		Kelch	611..657	CDD:128874