Protein Alignment CG7102 and Keap1

DIOPT Version :10

• Sequence 1: NP_787994.1
• Gene: CG7102 / 34079
• FlyBaseID: FBgn0031961
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_732202.2
• Gene: Keap1 / 42062
• FlyBaseID: FBgn0038475
• Length: 776
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 127/643 - (19%)
• Similarity: 203/643 - (31%)
• Gaps: 228/643 - (35%)

  Fly    28 RDERIYAHRLMLMARCKSFKT-----AKRGEVCRIPGCTVSPAAPGASTPTTIRLPHVNPELFRQ 87
            :.|...||:::|.|....||.     .|..|:.|                  ::|..|.|....:
  Fly    97 KKELFPAHKVVLSAASPYFKAMFTGGLKESEMSR------------------VQLQGVCPTAMSR 143

  Fly    88 FILYVYTAKLVLQDSQVFQMMILAQDIGVVELRTACEDHVISTLSVDNACTFLTAVMDIHEKAGA 152
            .:.::||.::.:.:..|.|::..|....|..:..||             |.||...:|.....|
  Fly   144 ILYFMYTGQIRVTEVTVCQLLPAATMFQVPNVIDAC-------------CAFLERQLDPTNAIG- 194

  Fly   153 KCAASFMER--CI-------IYIGENANECVKTNAFLTLTKDAIIKIISSDYFCLEEE-EVWRCV 207
              .|.|.|:  |:       ::|..|..:..:...||.|:...:|.:|..|...::|| ||:..|
  Fly   195 --IAHFAEQHGCVELQKKANVFIERNFTQVCQEEEFLQLSAYQLIALIRRDELNVQEEREVYNAV 257

  Fly   208 LSWAKYQAGVTQPTAHWTEEERARVCQHLSGVMGHVRLLLIDSQVFAEEVEPTGA---VP--MEL 267
            |.|.||             :|..|.|: :..::|.||...:......|:::....   ||  .|.
  Fly   258 LKWVKY-------------DEDNRHCK-MEHILGAVRCQFLTPNFLKEQMKNCDVLRKVPACREY 308

  Fly   268 SLERYRYAALH----ANKMMDNDKRLQPRLAVAVNMFPGS-QILKN---DNLALQTVLNNWV--- 321
            ..:.::...||    ..:...|..|:   :.||...|..| .||:.   |::...|:.|..:
  Fly   309 LAKIFKDLTLHKCPGVKERTPNTTRM---IFVAGGFFRHSLDILEAYNVDDMTWTTLANLRIPRS 370

  Fly   322 GVGKQSWRLVF-----RASTHG--YDSGAFHRY---------CDGVAPCMV----IGLGSHGEIS 366
            |:|....:..|     |.:..|  |||....||         |   ||..|    :|:....|:.
  Fly   371 GLGAAFLKGKFYAVGGRNNNIGSSYDSDWVDRYSAVTETWRPC---APMSVPRHRVGVAVMDELM 432

  Fly   367 ---GGYTDVAWAKT-------------------SRKGGYVQSERAFLFALNPANGEQPVKFDIVK 409
               ||...:.:..|                   .|.|..|......|:|:...:|.:       :
  Fly   433 YAVGGSAGMEYHNTVEYYDPDLDRWTLVQPMHAKRLGVGVVVVNRLLYAIGGFDGNE-------R 490

  Fly   410 KPYAICYHPD------CGPI----FGAGADLLISSNCNTNMDSYSNLPHSYDGT----------- 453
            .....||||:      ..|:    .|||.         ..::.|..:...:|||
  Fly   491 LASVECYHPENNEWSFLPPLQTGRSGAGV---------AAINQYIYVVGGFDGTRQLATVERYDT 546

  Fly   454 ---------------NAAHLTL----------FGDYNF--------------------------- 466
                           :|..||.          |...||
  Fly   547 ENDTWDMVAPIQIARSALSLTPLDEKLYAIGGFDGNNFLSIVEVYDPRTNTWTTGTPLKSGRSGH 611

  Fly   467 ------------TITDYEVYTLSSPAGSSNSGANHSNNQNLNHSTNGQAPGVPTKAKY 512
                        |..|||......|.||:|...|....||...|.:...||..:..::
  Fly   612 ASAVIYQPACSTTFMDYEDSDAPHPDGSNNGERNAHTPQNTYGSGSPHYPGTASNMQF 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7102	NP_787994.1	BTB_POZ_ZBTB_KLHL-like	20..112	CDD:349497	17/88 (19%)
		BACK	143..255	CDD:197943	29/121 (24%)
		TLDc	303..477	CDD:214733	53/307 (17%)
Keap1	NP_732202.2	PHA03098	92..599	CDD:222983	113/571 (20%)
		KELCH repeat	369..416	CDD:276965	12/49 (24%)
		KELCH repeat	420..463	CDD:276965	5/42 (12%)
		KELCH repeat	467..510	CDD:276965	10/49 (20%)
		KELCH repeat	514..558	CDD:276965	7/52 (13%)
		KELCH repeat	561..606	CDD:276965	6/44 (14%)