Protein Alignment CG14535 and KINESIN-12B

DIOPT Version :10

• Sequence 1: NP_609156.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_189009.2
• Gene: KINESIN-12B / 821947
• AraportID: AT3G23670
• Length: 1313
• Species: Arabidopsis thaliana
• Alignment Length: 1287
• Identity: 254/1287 - (19%)
• Similarity: 431/1287 - (33%)
• Gaps: 372/1287 - (28%)

  Fly    24 PPMPPT-------LIRRLSSRECYGVG----KVKVMLRVADRDRNSGGTEPDFMALDKKKRQVTL 77
            ||.||:       ||...::.....:|    .|||::|:..   .|.|.|.:.:........:|:
plant    65 PPRPPSSNPLKRKLIAEATADNGVAIGVSDSGVKVIVRMKP---PSKGEEEEMIVKKISNDALTI 126

  Fly    78 TDPRTACPPPQAAQERAPMVAAPKMFAFDNLFTGEDKQSDVCASALSEVIPAVLEGSDGCLLAMG 142
            .:                     :.|.||::...|..|.::.....:.::...|.|.:..:.|.|
plant   127 NE---------------------QTFTFDSIADPESTQDEIFQLVGAPLVENCLAGFNSSVFAYG 170

  Fly   143 YPATGQAQTVLGELGGGSGSGSASGSGVACSLGAAPCAIAWLYKGIQERRQKSGAR---FSVRVS 204
            ...:|:..|:.|. ..|......||.    ..|..|.....|:..:.|.:.|...|   :..|.|
plant   171 QTGSGKTYTMWGP-ANGLLEEHLSGD----QRGLTPRVFELLFARLSEEQAKHAERQLKYQCRCS 230

  Fly   205 AVGVSATKPDALSQDLLISHAAESDDSPGIYLRDDFLGGPTELRAPTAERAALFLDSALAGRLKS 269
            .:.:...:...|....|.:.....|...|:|:.:     .||......:..:..|...||.|...
plant   231 FLEIYNEQITDLLDPSLKNLMIREDVKSGVYVEN-----LTEEYVKNLKDLSKLLVKGLANRRTG 290

  Fly   270 SGSTASGSSGCAAPLESALIFTLHVYQYSLSRKGGVAGGR-SRLHIIDLGGCANR---------- 323
            :.|..:.||      .|..:||..|..:..|...|::..: ||::::||.|...:
plant   291 ATSVNAESS------RSHCVFTCVVESHCKSVADGLSSFKTSRINLVDLAGSERQKLTGAAGDRL 349

  Fly   324 ----NGGLPLSGIGNI--LLAILS---GQRHPPHKDHPLTPLLKDCLAPITCHVAIVAHVRPEQS 379
                |....||.:||:  :||.:|   .|||.|::|..||.||::.|.. ...:|:|..|.|.||
plant   350 KEAGNINRSLSQLGNLINILAEISQTGKQRHIPYRDSRLTFLLQESLGG-NAKLAMVCAVSPSQS 413

  Fly   380 YQ-DALSTIQIASR------------------------IHRLRRRKHRV--------PMPLA--- 408
            .: :..||::.|.|                        |.:||....||        ..|.|
plant   414 CRSETFSTLRFAQRAKAIQNKAIVNEVMQDDVNFLREVIRQLRDELQRVKDDKGNNPTNPNAAYT 478

  Fly   409 --------VGLAQGLG-GNGSSAGSGADPSSSEISADTVIYMGPNDDATD------GEHPPVYLP 458
                    :.|.:..| |:..|..:|.|...:|:..|        ::|.:      |..||
plant   479 TSWNARRSLSLLRSFGLGHPKSLPNGDDDGDTEMEID--------EEAVERLCAQMGLSPP---- 531

  Fly   459 SLTAGDNRGVMSKALK-GSGLEKPPSKSASNSPMMMKKAMAA----------------------- 499
               |.||...||:..| .|.|:....|..|.:...:|.:.|.
plant   532 ---AEDNNQEMSRVEKINSSLQTVVLKDESYNNSHLKSSEATDVNMEDACCQTENNGSETDNALT 593

  Fly   500 ------EKAKKLPGSHTGSLKRQAGAGACSSPMIPHEQPQIQAMGSPIPIPRHMVSKGSMVPSPK 558
                  :.:...|.|.|.||.      :|.|.......|                ||...:||.:
plant   594 VAETMDDGSSVQPDSITNSLH------SCISDTNQGNSP----------------SKAENIPSCQ 636

  Fly   559 GSPMRRAHPGAALEQLEAGMRKI---------TEEQWID--GPRVSRAKVAEARHLMREVNHVKQ 612
            ..            .:||.:..|         ||:..::  .|.:|.|.|:        |:.|..
plant   637 DL------------VIEADVSAIVSVADTSNNTEQVSVNPVSPCLSVAPVS--------VSPVLI 681

  Fly   613 CETWVDGPKSQSCR-SLTACNLPAAGGSQTQGYGFMDAHKKTMIRQWVENQ-TTQVFQSTVSASN 675
            ..|....||.::.| ||...::..|.             :|.:.|   .|| |.:|.:.:.:.|.
plant   682 PPTESASPKIRNSRKSLRTTSMSTAS-------------QKDIER---ANQLTPEVVEPSPAMST 730

  Fly   676 SPTALHWKLSQLKQKSLDLPDRPAF-----------NPEPSLDLNQPCFE-SLPLLDPAPPDGDE 728
            ....|:..||..|.::..:|.|...           :...|..|.:..|. |...|:..|.....
plant   731 EVLNLYSALSTKKSEAFPVPTRQLAASLHRGMKLLDSYRQSTALRRSTFRLSYKALECKPSTVLS 795

  Fly   729 DEDSGPSEVPPALPLLDDPLGSRDISQDNLHRML-SRHVSREQLHEAELVASRASSSHHP---SQ 789
            ..|.|....|.|          .:|::||...:| ||...|.:. :|:.::..::....|   |:
plant   796 KADVGVQTYPQA----------DEIAEDNSKEVLCSRCKCRAEC-DAQEISDTSNLQLVPIDNSE 849

  Fly   790 RSIDCGLQV---TEEEIARTMSRDRDHDPSAHPLSALSHC-DNISFVSSFNMACESFS---ECGE 847
            .|.....||   .|:.:|.::.|:         ::....| ...|.:|..|...:.:.   ||..
plant   850 GSEKSNFQVPKAVEKVLAGSIRRE---------MAMEEFCTKQASEISQLNRLVQQYKHERECNA 905

  Fly   848 RARQ-QFDQLARLHEIFTSQLA---------------------MAEVTPSAALFRTDIGSVFSE- 889
            ...| :.|::.||..:....|:                     |.|..|.....|.::..|..|
plant   906 IIGQTREDKIVRLESLMDGVLSKDDFLDEEFASLMHEHKLLKDMYENHPEVLQTRIELKRVQEEL 970

  Fly   890 ---PVYHFNVGQSSVCSEPAYRLTPS----PPKQPSHSPSQGSL------------PSLNGIMEI 935
               ..::.::|:..|..|..:.|...    .....:.:..:|||            |.||.|.|
plant   971 ESFKNFYGDMGEREVLLEEIHDLKAQLQCYTDSSLTSARRRGSLLKLTYACDPNQAPQLNTIPE- 1034

  Fly   936 AGMDDYALLRQPDGASDPNLQKGEKRFTPQHDD--------ICELDEKSMAAAVGKGNSLEDAQH 992
                      ..|...:..|::...|:|....:        ..|||...:.....| ..|:..:.
plant  1035 ----------SVDEGPEKTLEQERLRWTEAESNWISLAEELRTELDTNRLLMEKQK-RELDTEKR 1088

  Fly   993 KLNEITNILPLAAQSRLPLLPLNTSSEAYDSGHDSNSTPRTSKHSGISRRAESGYHSVATVRDSD 1057
            ...|:|..:.:|.|....::      |.| :..:.......::|    ||...|      :.|..
plant  1089 CAEELTEAMQMAMQGHARMI------EQY-ADLEEKHIQLLARH----RRIREG------IDDVK 1136

  Fly  1058 ESSFASGMSKGQRHRITVSGTGAVTSAGIGNYQRQCHKKRHRQDQAGNNKGL 1109
            :::..:|: ||...|. ::...|..||  ...||: .:.|:.:|:   ||.|
plant  1137 KAAARAGV-KGAESRF-INALAAEISA--LKVQRE-KEVRYFRDE---NKSL 1180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14535	NP_609156.1	Motor_domain	44..394	CDD:473979	84/397 (21%)
KINESIN-12B	NP_189009.2	PLN03188	1..1313	CDD:215621	254/1287 (20%)