Protein Alignment CG14535 and Kif26a

DIOPT Version :9

• Sequence 1: NP_001285726.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_006516225.1
• Gene: Kif26a / 668303
• MGIID: 2447072
• Length: 1913
• Species: Mus musculus
• Alignment Length: 1375
• Identity: 365/1375 - (26%)
• Similarity: 536/1375 - (38%)
• Gaps: 385/1375 - (28%)

  Fly     2 ATTSTSNMSRNGGFCGALQRAPPPMPPTLIRRLS--SRECYGVGKVKVMLRV-----ADRDRNSG 59
            :|..||....:  |.|:||..|||:||.|:|..|  .......||||||||:     ..|...|
Mouse   354 STRGTSTYPTD--FSGSLQLWPPPVPPCLLRAASKAKENPSSFGKVKVMLRIWPAQGVQRSAES- 415

  Fly    60 GTEPDFMALDKKKRQVTLTDPRTACPPPQAAQERAPMVAAPKMFAFDNLFTGEDKQSDVCASALS 124
               ..|:.:|.:|:||||.|| .|.||..|....||....|||||||.:|..:.:|::||:..::
Mouse   416 ---TSFLKVDSRKKQVTLYDP-AAGPPGCAGLRHAPTAPVPKMFAFDAIFPQDSEQAEVCSGTVA 476

  Fly   125 EVIPAVLEGSDGCLLAMGYPATGQAQTVLGELGGGSGSGSASGSGVACSLGAAPCAIAWLYKGIQ 189
            :|:.:|:.|:|||:.:.|:.:.|::.|::|:            .....|||..||||:||::.|.
Mouse   477 DVLQSVVSGADGCIFSFGHMSLGKSYTMIGK------------DSSPQSLGIVPCAISWLFRLID 529

  Fly   190 ERRQKSGARFSVRVSAVGVSATKPDALSQDLL---ISHAAESDDSPGIYLRDDFLGG-----PTE 246
            ||:::.|.|||:|||||.|..  .|...:|||   .|.:.:...|||:|||:|.:.|     ..|
Mouse   530 ERKERLGTRFSIRVSAVEVCG--HDQSLRDLLAEVASGSLQDTQSPGVYLREDPVCGTQLQNQNE 592

  Fly   247 LRAPTAERAALFLDSALAGRLKSSGSTASGSSGCAAPLESALIFTLHVYQYSLSR--KGGVAGGR 309
            |||||||:||.:||:|||.|     ||:....|..|...|.::||||||||.:.:  :||::|||
Mouse   593 LRAPTAEKAAFYLDAALAAR-----STSRAGCGEEARRSSHMLFTLHVYQYRVEKCGQGGMSGGR 652

  Fly   310 SRLHIIDLGGC-------ANRNGG---LPLSGIGNILLAILSGQRHPPHKDHPLTPLLKDCLAPI 364
            ||||:||||.|       ...:||   |.||.:|:::||:::|.:|.|::||.||.||::.||..
Mouse   653 SRLHLIDLGSCDAAVGRGGEASGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESLATT 717

  Fly   365 TCHVAIVAHVRPEQSYQ-DALSTIQIASRIHRLRRRK-----------------------HRVPM 405
            .|...::||:....::. :.|||:|:|:|||||||:|                       |..|.
Mouse   718 NCRTTMIAHISDSPAHHAETLSTVQLAARIHRLRRKKGKHASSSSGGESSCEEGRARRPPHLRPF 782

  Fly   406 -PLAVGL-----AQGLGGNGSSAGSGADP---SSSEISADTVIYMGP------NDDATDGEHPPV 455
             |.||.|     |.||.|         ||   ||||.|.|||||:||      :.:.||.|.||.
Mouse   783 HPRAVVLDPDRSAPGLSG---------DPDYSSSSEQSCDTVIYVGPGGMALSDRELTDNEGPPD 838

  Fly   456 YLPSLTAGDNRGVMSKALKGSGLEKPPSKSASNSPMMMKKAMAAEKAKKLPGSHTGSLKRQAG-A 519
            ::|.:.|      :|:.....|.........|....:.::....:.::..||...||...||. |
Mouse   839 FVPIIPA------LSRRRPSEGPRDADHFRCSTFAELQERLECIDGSEAFPGPQGGSDGAQASPA 897

  Fly   520 GACSSPMIPHEQPQIQAMGSPIPIPRHMVSKGSMVPSPKGSPMRRAHPGAALEQLEAGMRKITEE 584
            .....|.:|...|..:|:...:           :...|:|||....|..|: :..:.|.:   .|
Mouse   898 RGGRKPSLPEATPSRKAVAPTV-----------VTSCPRGSPGHDTHRSAS-DPSKTGTQ---SE 947

  Fly   585 QWIDG---------------------------PRVSRAK-------------------------- 596
            |.:||                           ||...|:
Mouse   948 QRVDGSRPEPPASDKTSGGGGRRPLPSPAPPPPRQPEAQGIPKEPGGEGTDSVLRTPPVGMSGQA 1012

  Fly   597 --------------VAEARHLMR-------------EVNHVKQCETWV----------DGPKSQS 624
                          .|..|||.|             |:|...:....|          ...:..|
Mouse  1013 ALPPLLSDSAYLSPSARGRHLERGLLTTTVTLQQPVELNGEDELVFTVVEELPLGGLAGATRPSS 1077

  Fly   625 CRSLTA-CNLPA-AGGSQTQGYGFMDAHKKTMIRQWVENQTTQVFQSTVSASNSPTALHWK---- 683
            ..|::: |:|.| |.||:....       .:.|....:..|:|:.:........|....|.
Mouse  1078 LASMSSDCSLQALASGSRPVSI-------ISSINDEFDAYTSQMSEGPGDPGEFPEGTAWAGGSP 1135

  Fly   684 ----LSQLKQKSLDLPDRPAFNPEPSLDLNQPCFESLPLLDPAPPD----GDEDEDSGPSEVPPA 740
                .|.|....:.|.:.....|:|....|...       .|.||:    |...|:|........
Mouse  1136 ASSIGSWLSDVGVCLSESRGPTPQPPFSPNSAA-------GPGPPEFPTPGSSLEESKVRSSECG 1193

  Fly   741 LPLLDDPLGSRDISQDNLHRMLSRHVSREQLHEAELVASR---------ASSSHH-PSQRSIDCG 795
            .|  |:|..:|                  .||..|.||:.         |.|.|. .|.::|...
Mouse  1194 RP--DNPGSAR------------------SLHPGEAVATTQTQPGREPWARSPHEVASAQTIHSS 1238

  Fly   796 LQVTEEEIARTMSRDRDHDPSAHPLS-----------ALSHCDNISFVSS--------------- 834
            |. .:.....|.||.|   ||..|.|           ....||.....|:
Mouse  1239 LP-RKPRTTSTASRAR---PSRGPYSPGGLFEDPWLLRAEDCDTRQIASTGRAPSPTPGSPRLPE 1299

  Fly   835 --FNMACE----SFSECGERARQQFDQLARLHEIFTSQLAMAEVTPSAALFRTDIGSVFSEPVYH 893
              ..:||.    ...|...|..::.:.:||:..:......:...||:|:     .|...:|.|.|
Mouse  1300 TQMMLACAQRVVDGCEVASRMSRRPEAVARIPPLRRGATTLGVTTPAAS-----CGDAPAEAVVH 1359

  Fly   894 ------FNVGQSSVCSEPAYRLTPS---PPKQPSHSPSQGSLPSLNGIMEIAGMDDYALLRQPDG 949
                  .:..:.||..:.|:...||   ||..|....|.....:|.....:      .|.|
Mouse  1360 SGSLKTTSGSKKSVSPKGAFFPRPSGAGPPAPPVRKSSLEQSTALTPTQAL------GLTR---- 1414

  Fly   950 ASDPNLQKGEKRFTP--QHDDICELDEKSMAAAVGKGN---------SLEDAQ---HKLNEITNI 1000
            |..|:..:||:...|  :.|........|:.|..||.:         |||..:   |..:::.::
Mouse  1415 AGAPSAFRGEEEARPSGRSDSSVPKATSSLKARAGKMDVPYRPSGHMSLERCEGLAHGSSKVRDV 1479

  Fly  1001 L--PLAAQSRL-------PL--LPLNTSSEAYDSG---------HDSNSTPRTSKHSGISRRAES 1045
            :  |..|..||       ||  .|...:|.|...|         ...|..|.||:..|
Mouse  1480 VGRPPRAVPRLGVPSASPPLGPAPACRNSPAKGVGATKPPAGGAKGRNLGPSTSRALG------- 1537

  Fly  1046 GYHSVATVRDSD--ESSFASGMSKGQRHR-ITVSGTGAVTSAG--IGNYQ--RQCHKKRHRQDQA 1103
                 |.|:...  ....|.|...|.|.. ..|.|.||....|  :|..|  |..|.:.|....:
Mouse  1538 -----APVKPLGPVAGKTAGGAVPGPRAAPRAVPGIGAKAGRGTIMGTKQAFRAAHSRVHELAAS 1597

  Fly  1104 GN-NKGLCNW 1112
            |: ::|..:|
Mouse  1598 GSPSRGGLSW 1607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14535	NP_001285726.1	Motor_domain	44..394	CDD:277568	151/375 (40%)
Kif26a	XP_006516225.1	KISc	396..748	CDD:276812	151/375 (40%)
		PRK07764	<869..1301	CDD:236090	84/484 (17%)
		PHA03247	<1154..1647	CDD:223021	108/512 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	230	1.000	Domainoid score	I2446
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002018
OrthoInspector	1	1.000	-	-		otm42323
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24115
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4619
SonicParanoid	1	1.000	-	-		X1937
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.900