Protein Alignment CG14535 and Khc-73

DIOPT Version :9

• Sequence 1: NP_001285726.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_001261000.1
• Gene: Khc-73 / 36718
• FlyBaseID: FBgn0019968
• Length: 1957
• Species: Drosophila melanogaster
• Alignment Length: 984
• Identity: 202/984 - (20%)
• Similarity: 339/984 - (34%)
• Gaps: 312/984 - (31%)

  Fly    44 KVKVMLRVADRDRNSGGTEPDFMALDKKKRQVTLTDPRTACPPPQAAQERAPMVAAPKMFAFDNL 108
            |:||.:||  |..|....|.|...:.:.::|.|:...    |||....||    ..||.||||:.
  Fly     5 KIKVAVRV--RPFNRREIELDTKCIVEMEKQQTILQN----PPPLEKIER----KQPKTFAFDHC 59

  Fly   109 FTGEDKQSDVCASALS-------EVIPAVLEGSDGCLLAMGYPATGQAQTVLGELGGGSGSGSAS 166
            |...:.:.:..||..:       .::....:|.:.|:.|.|...:|::.|::
  Fly    60 FYSLNPEDENFASQETVFDCVGRGILDNAFQGYNACIFAYGQTGSGKSYTMM------------- 111

  Fly   167 GSGVACSLGAAPCAIAWLYKGIQERRQKSGARFSVRVSAVGVSATKPDALSQDLLISHAAESDDS 231
              |...|.|..|.....|:..|..:.... ..:.|.||.:.:...|    ..|||       |..
  Fly   112 --GTQESKGIIPRLCDQLFSAIANKSTPE-LMYKVEVSYMEIYNEK----VHDLL-------DPK 162

  Fly   232 P---GIYLRDDFLGGP-----TELRAPTAERAALFLDSALAGRLKSSGSTASGSSGCAAPLESAL 288
            |   .:.:|:..:.||     ::|...:.:.    :|:.:....||  .|.:.::..|....|..
  Fly   163 PNKQSLKVREHNVMGPYVDGLSQLAVTSYQD----IDNLMTEGNKS--RTVAATNMNAESSRSHA 221

  Fly   289 IFTLHVYQYSLSRKGGVAGGR-SRLHIIDLGGC----------------ANRNGGLPLSGIGNIL 336
            :|::.:.|....:..||:|.: ||:.::||.|.                :|.|..|...|   ::
  Fly   222 VFSVVLTQILTDQATGVSGEKVSRMSLVDLAGSERAVKTGAVGDRLKEGSNINKSLTTLG---LV 283

  Fly   337 LAILSGQ---------RHPPHKDHPLTPLLKDCLAPITCHVAIVAHVRPE-QSYQDALSTIQIAS 391
            ::.|:.|         :..|::|..||.||||.|.. .....:||.:.|. .:|::.|||::.|.
  Fly   284 ISKLADQSNGKKSGNDKFVPYRDSVLTWLLKDNLGG-NSRTVMVATISPSADNYEETLSTLRYAD 347

  Fly   392 RIHR---------------LRRRKHRVP-----MPLAVG---------LA--------------- 412
            |..|               :|..:|.|.     :..|.|         ||
  Fly   348 RAKRIVNHAVVNEDPNARIIRELRHEVETLRSMLKHATGSPVGDVQDKLAESENLMKQISQTWEE 412

  Fly   413 -------------QGLGGNGSSA-GSG--------------ADPSSSEISADTVIYMGPNDDAT- 448
                         |.|...|.|. .||              ||||.:|:   .|.|:   .|.|
  Fly   413 KLVKTERIQNERQQALEKMGISVQASGIKVEKNKYYLVNLNADPSLNEL---LVYYL---KDRTL 471

  Fly   449 ------DGEHPPVYLPSLTAGDNRGVMSKALKGSGLEKPPSKSAS---NSPMMMKKAMAAEKAKK 504
                  .|:.|.:.|..|.......|::  ::.|||...|.:.|.   |....::|.......:.
  Fly   472 IGGRTISGQQPDIQLSGLGIQPEHCVIT--IEDSGLYMEPVQGARCFVNGSAAVEKTPLQNGDRI 534

  Fly   505 LPGSH----TGSLKRQAGAGACSSPMIP----------HEQPQIQAMGSPIPIP------RHMVS 549
            |.|:|    ..|.|....:...|.|..|          .|..|.:....||...      :|...
  Fly   535 LWGNHHFFRVNSPKSNNTSMCASEPQTPAQLIDYNFARDEIMQNELSNDPIQTAIARLERQHEED 599

  Fly   550 KGSMVPSPKG-------------SPMRRAHPGAALEQLEAGMRKITE---------EQWI-DGPR 591
            |...:...:.             ||.....|.|..:.|..|  |||.         |:|. :...
  Fly   600 KQVALEKQRQEYERQFQQLRNILSPSTPYAPYAPYDPLRMG--KITPNTPTSQMRVEKWAQERDE 662

  Fly   592 VSRAKVAEAR-HLMREVNHVKQCETWVDGPKSQSCRSLTACNLPAAGGSQTQGYGFMDAHKKTMI 655
            :.|..:.:.: .:||..:.|::.....:..:.::..|:| ..:|.|..|..:..|...:....::
  Fly   663 MFRRSLGQLKTDIMRANSLVQEANFLAEEMEKKTKFSVT-LQIPPANLSPNRRRGAFVSEPAILV 726

  Fly   656 RQWVENQTTQVFQSTVSASNSPTALHWKLSQLKQKSLDLPDRPAFNPEPSLDLNQPCFESLPLLD 720
            ::  .|..:|:               |.:.:|:.|.:|:  |..:.......||
  Fly   727 KR--TNSGSQI---------------WTMEKLENKLIDM--REMYQEHKERVLN----------- 761

  Fly   721 PAPPDGDEDEDSGPSEVPPALPLLDDPLGSRDISQDNLHRMLS-RHVSREQL-HEAELVASRASS 783
                 |.:::::.|          .||...   ||:| |.::. .::..|.| |:.:|      .
  Fly   762 -----GLDEDNAKP----------QDPFYE---SQEN-HNLIGVANIFLEVLFHDVKL------D 801

  Fly   784 SHHP--SQRSIDCG-LQVTEEEIARTMSRDRDHDPSAHPLSALSHCDNISFVSSFNMACESFSEC 845
            .|.|  ||:....| |||..|.||..|.:||                          .|||.||.
  Fly   802 YHTPIISQQGEVAGRLQVEIERIAGQMPQDR--------------------------MCESVSES 840

  Fly   846 GERARQQFD 854
            ...:|.::|
  Fly   841 SGDSRDEYD 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14535	NP_001285726.1	Motor_domain	44..394	CDD:277568	90/391 (23%)
Khc-73	NP_001261000.1	KISc_KIF1A_KIF1B	4..359	CDD:276816	91/400 (23%)
		KISc	6..359	CDD:214526	90/399 (23%)
		Kinesin_assoc	356..468	CDD:292801	20/117 (17%)
		FHA	446..546	CDD:238017	24/107 (22%)
		KIF1B	741..786	CDD:289208	14/76 (18%)
		DUF3694	<1196..1252	CDD:289256
		CAP_GLY	1786..1850	CDD:279625

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100