Protein Alignment CG14535 and vab-8

DIOPT Version :9

• Sequence 1: NP_001285726.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: NP_506063.2
• Gene: vab-8 / 179675
• WormBaseID: WBGene00006874
• Length: 1066
• Species: Caenorhabditis elegans
• Alignment Length: 1166
• Identity: 239/1166 - (20%)
• Similarity: 399/1166 - (34%)
• Gaps: 398/1166 - (34%)

  Fly   105 FDNLFTGEDKQSDVCASALSEVIPAVLEGSDGCLLAMGYPATGQAQTVLGELGGGSGSGSASGSG 169
            ||::|..:..|.|:..:.||:.|.:|..|:|..:||||....|:.:.:.|        .|.|.:|
 Worm    57 FDHIFRTDATQDDMYTAFLSDTINSVFAGNDATVLAMGAKTNGKDERLYG--------NSVSRNG 113

  Fly   170 VACSLGAAPCAIAWLYKGIQERRQKSGARFSVRVSAVGVSATKPDALSQDLLISHAAESDDSPG- 233
            :      ...||..|...:.:.:. |..|..||:||:.||..:...:  |||      |..:|.
 Worm   114 L------VQMAITQLMNALDDNKD-SEERIQVRMSAIMVSQNESSIV--DLL------SPFNPDP 163

  Fly   234 ----IYLRDD-----FLGGPTELRAPTAERAALFLDSALAGRLKSSGSTASGSSGCAAPLESALI 289
                :.:.||     |:...:|:|..|.::|..:|::|:..|:.....|..         .|.:.
 Worm   164 RHRVVKIVDDARTGVFIDNESEIRVETIDQALFYLNTAVDHRMIQDEHTHR---------TSHVF 219

  Fly   290 FTLHVYQYSLSRKGGVAGGRSRLHIIDLG-GCAN-RNGGLPLSGIGNILLAILSGQRHPPHKDHP 352
            .:|.:|.|.:..|  :.|||.||..:|:| |..| .|||:.:..:|:||||::...:|.|.:|..
 Worm   220 ISLSLYSYKMGDK--MQGGRRRLCFLDMGIGERNSTNGGMTMPALGSILLAMVQRNKHIPSRDSS 282

  Fly   353 LTPLLKDCLAPITCHVAIVAHVRPEQSYQDALSTIQIASRIHRLRRRKHRVPMPLAVGLAQGLGG 417
            :..|:: |....:.....|.....:.  .|..:...:|.:|.|.|.:.       .||..:...|
 Worm   283 VCQLIR-CALSTSRFTTFVFSFGAKS--DDNENIAHLACKIARTRAKS-------MVGHGRKSSG 337

  Fly   418 ---------NGSSAGS-----GADP---------SSSEIS-ADTVIYMGPNDDATDGEHPPVYLP 458
                     |.||.|:     |..|         |.||:| |:|||::|||...|
 Worm   338 TMSTGTMESNSSSCGTTTITPGGTPRTQRRFELESGSELSAAETVIFLGPNSSRT---------- 392

  Fly   459 SLTAGDNRGVMSKALKGSGLEKPPSKSASNSPMMMKKAMAAEKAKKLPGSHTGSLKRQAGAGACS 523
                                ..|.|.:...:|..::......:      :|:|
 Worm   393 --------------------ASPASTTMPFTPTSIRPLHRTTR------NHSG------------ 419

  Fly   524 SPMIPHEQPQIQAMGSPIPI-----PRHMVSKGSMVPSPKGSPMRRAHPGAALEQLEAGMRKITE 583
                      ::|:..|:.:     |.|....|.:...|   ||.|.|    ...|.|.::  ..
 Worm   420 ----------VEALSKPLSVETKSSPTHNCHDGCIHSIP---PMLRGH----TPFLSASLK--LY 465

  Fly   584 EQWIDGPRVSRAKVAEARHLMREVNHVKQCETWVDGPKSQSCRSLTACNLPAAGGSQT----QGY 644
            ::....|..|||..|.                                  |||.|.:|    :.:
 Worm   466 DELCSPPSSSRASPAP----------------------------------PAAFGGKTSEKREDF 496

  Fly   645 GFM-----------------DAHKKTMIRQWVENQTTQVFQSTVSASNSPTALHWKLSQLKQKSL 692
            |.|                 |..|...|.||:|            .|.:|..|
 Worm   497 GIMIAQPSIPLMKAKSKYNLDDGKMKQIMQWME------------TSEAPPIL------------ 537

  Fly   693 DLPDRPAFNPEPSLDLNQPCFE----------------SLPLLDPAPPDGDEDEDSGPSEVPPAL 741
                           .:.||:|                |.||.|...   .|:|....|......
 Worm   538 ---------------FSSPCYENSATSVEELRECVGILSHPLEDIIE---QEEESMRTSTATTGG 584

  Fly   742 PLLDDP---LGSRDIS----------QDNLHRMLSRHVSREQLHE--AELVASRASSSHHP---- 787
            ...|.|   |..:|::          ::.|..:::..:|..:.|:  |:|.|.|.:.:.:.
 Worm   585 SKKDHPLRILSKQDLNVEPEIKDKQEENELELVMAASLSSMRSHDILAKLEAMRNAQNGNSVQNI 649

  Fly   788 --SQRSIDCGLQVTEEEIARTMSR------DRDHDPSAHPLS-------ALSHCDNISFVSSFNM 837
              ||.:.|  :.|:|.::.|..|.      .|..:...:.|.       .|:.|...|.:||.:.
 Worm   650 GNSQSNTD--MDVSEMDVYRRASHLEEYAMQRVREIEENKLKNKKKIKLGLNCCQQQSMISSGST 712

  Fly   838 ACE--SFSECGERARQQFDQLARLHEIFTSQLAMAEVTP-----SAALF------RTDIGSVFSE 889
            ..:  ......|:.|:..::..| .|:...:.|..::|.     ...|.      :..|.:..:.
 Worm   713 VVDWSQIERKKEKEREVHEEEMR-KEMLRERRAKLKITELEIKRERNLIDKELDDKKGIANSIAR 776

  Fly   890 PVYHFNVGQSSVC-------SEPAYRLTP---SPPKQPSHSPSQ---GSLPSLNGIMEIAGMDDY 941
            .:.||::   |.|       |...:|:.|   |.|..|:.|..:   |||..|:.
 Worm   777 QLQHFSL---SPCRGGRTHRSVSTHRIDPPNASLPSTPTMSHKKVIGGSLAKLSA---------- 828

  Fly   942 ALLRQPDGAS-----DPNLQKGEKRFTPQHDDI----------CELDEKSMAA---AVGKGNSLE 988
                  .|||     .|:...|..:..|:|..:          .|.:.||..|   :..|...:.
 Worm   829 ------SGASGSTGAPPSPALGYHQSLPRHSKLPTSVNGRRASAERERKSNKASRNSCSKERKIS 887

  Fly   989 DAQHKLNEITNILPLAAQSRLPLLPLNTSSEAYDSGHDSNSTPRTSKHSGISRRAESGYHS--VA 1051
            .::.:|           |.|.|...: ||.::| .|..::|:.|.|...|      |.:.:  |:
 Worm   888 GSKEEL-----------QWRSPYAQM-TSPKSY-GGPGTSSSGRGSSAPG------SDFETPVVS 933

  Fly  1052 TVRDSDESSFASG---MSKGQRHRITVSGTGAVTSAGIGNYQRQCHKKRHRQDQAGNNKGL 1109
            |...|     |:|   .||.|.:    |.:....||...:.....:||.|..|:..|.:.|
 Worm   934 TTEKS-----ANGTIPRSKRQSY----SASSGYESANDYHIYSTTNKKPHILDKKRNEEKL 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14535	NP_001285726.1	Motor_domain	44..394	CDD:277568	77/300 (26%)
vab-8	NP_506063.2	Motor_domain	54..300	CDD:277568	74/277 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I5589
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7251
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002018
OrthoInspector	1	1.000	-	-		oto17247
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950