Protein Alignment CG14535 and Kif3a

DIOPT Version :9

• Sequence 1: NP_001285726.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Sequence 2: XP_006532388.1
• Gene: Kif3a / 16568
• MGIID: 107689
• Length: 725
• Species: Mus musculus
• Alignment Length: 597
• Identity: 139/597 - (23%)
• Similarity: 235/597 - (39%)
• Gaps: 117/597 - (19%)

  Fly    45 VKVMLRVAD-RDRNSGGTEPDFMALDKKKRQVTLTDPRTACPPPQAAQERAPMVAAPKMFAFDNL 108
            |||::|... .:|.........:::|:.:..:|:....::..|             ||.|.||.:
Mouse    15 VKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDSSNEP-------------PKTFTFDTV 66

  Fly   109 FTGEDKQSDVCASALSEVIPAVLEGSDGCLLAMGYPATGQAQTVLGELGGGSGSGSASGSGVACS 173
            |..|.||.||.......:|.:||||.:|.:.|.|...||:..|:         .|..:..|:.
Mouse    67 FGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTM---------EGVRAVPGLR-- 120

  Fly   174 LGAAPCAIAWLYKGIQERRQKSGARFSVRVSAVGV-SATKPDALSQDLLISHAAESDDSP--GIY 235
             |..|.:.|.::..|  .:.:...||.||||.:.: :....|.|.:|.  :...|..:.|  |:|
Mouse   121 -GVIPNSFAHIFGHI--AKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQ--TQRLEVKERPDVGVY 180

  Fly   236 LRDDFLGGPTELRAPTAERAALFLDSALAGRLKSSGSTASGSSGCAAPLESALIFTLHVYQYSLS 300
            ::|  |.......|...:|.     ..|..:.:|.|:|.......    .|..|||:.:   ..|
Mouse   181 IKD--LSAYVVNNADDMDRI-----MTLGHKNRSVGATNMNEHSS----RSHAIFTITI---ECS 231

  Fly   301 RKGGVAGG----RSRLHIIDLGGCAN--RNG------------GLPLSGIGNILLAILSGQ-RHP 346
            .| ||.|.    ..:||::||.|...  :.|            .|.||.:||::.|::.|: .|.
Mouse   232 EK-GVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHV 295

  Fly   347 PHKDHPLTPLLKDCLAPITCHVAIVAHVRP-EQSYQDALSTIQIASRIHRLRRRKHRVPMPLAVG 410
            |:::..||.||:|.|.. .....:.|::.| :.:|.:.:||::.|:|...::.:......|....
Mouse   296 PYRNSKLTRLLQDSLGG-NSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDAL 359

  Fly   411 LAQ---GLGGNGSSAGSGADPSSSEISADTVIYMGPNDDATDGEHPPVYLPSLTAGDNRGVMSKA 472
            |.|   .:.........|.:.|.|:||       |..:|..:||          .|:: |...|.
Mouse   360 LRQFQKEIEELKKKLEEGEEVSGSDIS-------GSEEDDEEGE----------LGED-GEKKKK 406

  Fly   473 LKGSGLEKPPSKSASNSPMMMKKAMAAEKAKKLPGSHTGSLKRQAGAGACSSPMIPHEQPQI--- 534
            .:||.     |.|:|:|...:.:....|           .|..|||....|...:...|.:|
Mouse   407 RRGSS-----SSSSSDSTCSVIEKPLDE-----------FLPHQAGKKKVSPDKMVEMQAKIDEE 455

  Fly   535 -QAMGSPIPIPRHMVSKGSMVPSPKGSPMRRAHP--GAALEQLEAGMRKITEEQWIDGPRVSRAK 596
             :|:.:.:.:.....:|.......:...:.:|..  .:.||:|.|..:|:     |.|.....||
Mouse   456 RKALETKLDMEEEERNKARAELERREKDLLKAQQEHQSLLEKLSALEKKV-----IVGGVDLLAK 515

  Fly   597 VAEARHLMREVN 608
            ..|...|:.|.|
Mouse   516 AEEQEKLLEESN 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14535	NP_001285726.1	Motor_domain	44..394	CDD:277568	94/372 (25%)
Kif3a	XP_006532388.1	KISc_KIF3	13..345	CDD:276822	94/374 (25%)
		SMC_N	<340..717	CDD:308206	46/227 (20%)
		SMC_prok_B	<449..>615	CDD:274008	18/84 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900