DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rack1 and rack1

DIOPT Version :9

Sequence 1:	NP_001260218.1	Gene:	Rack1 / 34070	FlyBaseID:	FBgn0020618	Length:	318	Species:	Drosophila melanogaster
Sequence 2:	NP_001004946.1	Gene:	rack1 / 448353	XenbaseID:	XB-GENE-5927078	Length:	317	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	245/315 - (77%)
Similarity:	276/315 - (87%)	Gaps:	1/315 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSETLQLRGTLIGHNGWVTQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSH 65
            |:|.:.|||||.|||||||||||.|:.||.|:|:|||||:|:||||||| ||||.||:.|.||||
Frog     1 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSSSRDKTVIMWKLTRDE-TNYGVPQRALRGHSH 64

  Fly    66 FISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTI 130
            |:||||:||||.:|||||||.|||||||..|.|||||.|||||||||||||||||||||||||||
Frog    65 FVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTI 129

  Fly   131 KLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGY 195
            ||||||..||:|:||:.||:||||||||||.|||||||||||:.||||||||||||.||.||:||
Frog   130 KLWNTLGVCKYTVQEESHTEWVSCVRFSPNSSNPIIVSCGWDKMVKVWNLANCKLKTNHIGHSGY 194

  Fly   196 LNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKIW 260
            |||||||||||||.|||||.:|:|||||:||:||||:..|:||||||||||||||.|.|||||||
Frog   195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDSGDVINALCFSPNRYWLCAATGPSIKIW 259

  Fly   261 DLACKKTVEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSV 315
            ||..|..|:||:.||:|.:|||:.|||.|||||.|||||||||:||.||||||::
Frog   260 DLEGKIIVDELKQEVISSSSKAEPPQCTSLAWSADGQTLFAGYTDNLIRVWQVTI 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rack1	NP_001260218.1	WD40	7..312	CDD:238121	240/304 (79%)
		WD40 repeat	18..62	CDD:293791	31/43 (72%)
		WD40 repeat	68..104	CDD:293791	28/35 (80%)
		WD40 repeat	109..145	CDD:293791	31/35 (89%)
		WD40 repeat	153..190	CDD:293791	32/36 (89%)
		WD40 repeat	196..232	CDD:293791	29/35 (83%)
		WD40 repeat	237..280	CDD:293791	31/42 (74%)
		WD40 repeat	287..311	CDD:293791	19/23 (83%)
rack1	NP_001004946.1	WD40	7..311	CDD:238121	240/304 (79%)
		WD40 repeat	18..61	CDD:293791	31/43 (72%)
		WD40 repeat	67..103	CDD:293791	28/35 (80%)
		WD40 repeat	108..144	CDD:293791	31/35 (89%)
		WD40 repeat	152..189	CDD:293791	32/36 (89%)
		WD40 repeat	195..231	CDD:293791	29/35 (83%)
		WD40 repeat	236..279	CDD:293791	31/42 (74%)
		WD40 repeat	286..310	CDD:293791	19/23 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4446
Inparanoid	1	1.050	527	1.000	Inparanoid score	I1211
OMA	1	1.010	-	-		QHG53895
OrthoDB	1	1.010	-	-		D372857at33208
OrthoFinder	1	1.000	-	-		FOG0003692
OrthoInspector	1	1.000	-	-		oto102788
Panther	1	1.100	-	-	LDO	PTHR19868
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R476
SonicParanoid	1	1.000	-	-		X2556
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110