DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7115 and Tab1

DIOPT Version :9

Sequence 1:	NP_001260216.1	Gene:	CG7115 / 34069	FlyBaseID:	FBgn0027515	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_079885.2	Gene:	Tab1 / 66513	MGIID:	1913763	Length:	502	Species:	Mus musculus

Alignment Length:	352	Identity:	82/352 - (23%)
Similarity:	134/352 - (38%)	Gaps:	105/352 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 QKTTEASIADIYTVQLNSAMRASGNLGAAKDSFLNNNNNGQNGAANAP------------PPNYE 284
            |..||.:.||:..|.|.:       ....:.|||.:.::.....|:..            ||.|:
Mouse    92 QLNTEHTEADVRRVLLQA-------FDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQ 149

  Fly   285 AKCYIEHGRINFGKLITDEIMSADYKLVEQAKRATN--IAGTTALIAIVQGSKLIVANVGDSRGV 347
                                     |::|:.|....  ..|..|::|::..|||.|||||.:|.:
Mouse   150 -------------------------KILERLKALEREISGGAMAVVAVLLNSKLYVANVGTNRAL 189

  Fly   348 M----YDWRGIAI-PLSFDHKPQQVRERKRIHDAG---GFIAFRGVWRVAGVLATSRALGDYPLK 404
            :    .|  |:.: .|:.||..:...|..|:...|   |.|...||  :.|..:| |.:|||.:|
Mouse   190 LCKSTVD--GLQVTQLNMDHTTENEDELFRLSQLGLDAGKIKQMGV--ICGQEST-RRIGDYKVK 249

  Fly   405 ----DKNL--------VIATPDILTFELNDHKPHFLILASDGLWDTF--------SNEE-ACTFA 448
                |.:|        :||.|:|...:..|....||:|.|:||:...        :|:| |....
Mouse   250 YGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMID 314

  Fly   449 LEHLKEPDFGA---------KSLAMESYKRGSV--------DNITVLVIVFKNDVYKIGSSAGKA 496
            .|..|:....|         |.:..:::..|..        :::|:||   :|..|.:|..:
Mouse   315 TEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERAKFCPRHEDMTLLV---RNFGYPLGEMS--- 373

  Fly   497 GEESLKVPAKSQPVAPAVVQRSNSIKT 523
              :....||....|.|..|..|::..|
Mouse   374 --QPTPTPAPGGRVYPVSVPYSSAQST 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7115	NP_001260216.1	PP2Cc	111..482	CDD:238083	72/309 (23%)
Tab1	NP_079885.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		PP2C	69..334	CDD:278884	67/278 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	414..476
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900