DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7115 and Ppm1l

DIOPT Version :9

Sequence 1:	NP_001260216.1	Gene:	CG7115 / 34069	FlyBaseID:	FBgn0027515	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_848841.2	Gene:	Ppm1l / 242083	MGIID:	2139740	Length:	360	Species:	Mus musculus

Alignment Length:	460	Identity:	156/460 - (33%)
Similarity:	220/460 - (47%)	Gaps:	125/460 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 LAYIWKLCRLYVLRPEVIF--C-GLILFVLLLYLQAVDVWSRSILGRIQATLGRQKAVKMMELSA 96
            |:.:.::.|.::||||.:|  | .|.|:....:...|....:|....::...|  |..::|:...
Mouse     9 LSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKG--KVAEIMQNDR 71

  Fly    97 SAG-------DHQSWEEMKQQSSAFAVLGRRPRMEDRFIIEENINNNTGISFFAVFDGHGGEFAA 154
            ..|       ..::||......:.:::.|||..|||||.:..::.|.|..|.|.:|||||||.||
Mouse    72 LGGLDVLEAEFSKTWEFKSHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAA 136

  Fly   155 DFAKDVLVKNIYNKIIEMSKLLKTEGNSGDYDKSPYLARKQSRKDANKENTEPTAGVMRKDSLRK 219
            ::.|..|.:                            |.||..:|..|:.
Mouse   137 EYVKSRLPE----------------------------ALKQHLQDYEKDK--------------- 158

  Fly   220 AHSTTADCSAIKQKTTEASIADIYTVQLNSAMRASGNLGAAKDSFLNNNNNGQNGAANAPPPNYE 284

Mouse   159 ----------------------------------------------------------------- 158

  Fly   285 AKCYIEHGRINFGKLITDEIMSADYKLVEQAKRATNIAGTTALIAIVQGSKLIVANVGDSRGVMY 349
                 |:..:.:..::..:|:|.|.:::|:...:.:.||||.|||::....|.||||||||||:.
Mouse   159 -----ENSVLTYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLC 218

  Fly   350 DWRGIAIPLSFDHKPQQVRERKRIHDAGGFIAFRGVWRVAGVLATSRALGDYPLKDKNLVIATPD 414
            |..|.|||||.||||.|::|||||..|||||:|.|.|||.|:||.||:|||||||:.|:||..||
Mouse   219 DKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPD 283

  Fly   415 ILTFELNDHKPHFLILASDGLWDTFSNEEACTFALEHLKEPDFGAKSLAMESYKRGSVDNITVLV 479
            ||||:|:..:|.|:|||||||||.||||||..|..|.|.||.|||||:.::|:.||..|||||:|
Mouse   284 ILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMV 348

  Fly   480 IVFKN 484
            :.|:|
Mouse   349 VKFRN 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7115	NP_001260216.1	PP2Cc	111..482	CDD:238083	136/370 (37%)
Ppm1l	NP_848841.2	PP2Cc	93..351	CDD:238083	136/370 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837318
Domainoid	1	1.000	207	1.000	Domainoid score	I2889
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H33158
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2818
Isobase	1	0.950	-	0	Normalized mean entropy	S2500
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1044139at2759
OrthoFinder	1	1.000	-	-		FOG0005078
OrthoInspector	1	1.000	-	-		oto93086
orthoMCL	1	0.900	-	-		OOG6_105716
Panther	1	1.100	-	-	LDO	PTHR13832
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6413
SonicParanoid	1	1.000	-	-		X119
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740