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Protein Alignment CG7115 and PHLPP1

DIOPT Version :9

Sequence 1:	NP_001260216.1	Gene:	CG7115 / 34069	FlyBaseID:	FBgn0027515	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_919431.2	Gene:	PHLPP1 / 23239	HGNCID:	20610	Length:	1717	Species:	Homo sapiens

Alignment Length:	594	Identity:	132/594 - (22%)
Similarity:	201/594 - (33%)	Gaps:	187/594 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 KLCRLYVLRPEVIFCGLILFVLL---------------LYLQAVDVWSRSILGRIQATLGRQKAV 89
            ::|.|    |..:||...|..||               ..::.:||....:|......|  .||.
Human   928 QICEL----PARLFCNSSLRKLLAGHNQLARLPERLERTSVEVLDVQHNQLLELPPNLL--MKAD 986

  Fly    90 KMMELSASAGDHQSWEEMKQQSSAFAVLGRRPRMEDRFIIEENINNNTGISFFAVFDGHGGEFAA 154
            .:..|:|||.        |.:|...|.|..    |...|::|....|..::
Human   987 SLRFLNASAN--------KLESLPPATLSE----ETNSILQELYLTNNSLT-------------- 1025

  Fly   155 DFAKDVLVKNIYNKIIEM----------SKLLKTEGNSGDYDKSPYLARKQSRKDANKENTEPTA 209
            |....:|..:.:.||:.|          ||:.|.| ...:.|.|           .||....||.
Human  1026 DKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLE-ELEEIDLS-----------GNKLKAIPTT 1078

  Fly   210 GVMRKDSLRKAHSTTA----------------------DCSAIKQKTTEAS-------------- 238
             :|   :.|:.|:..|                      .|:.:.:.|...:
Human  1079 -IM---NCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGNP 1139

  Fly   239 --IADIYTVQLNSAMR-----------ASG-----NLGAAKDSFLNN---------NNNGQN--- 273
              :.|..|::|.:.:|           |||     :.|..:.|.:.|         ||...|
Human  1140 RLVLDHKTLELLNNIRCFKIDQPSTGDASGAPAVWSHGYTEASGVKNKLCVAALSVNNFCDNREA 1204

  Fly   274 ------GAANAPPPNYEAKCYIEHGRINFGKLITDEIMSA----DYK----LVEQAKRAT---NI 321
                  |..|...| |..:|       ....::.:|:...    :|.    :|.|.|..|   .:
Human  1205 LYGVFDGDRNVEVP-YLLQC-------TMSDILAEELQKTKNEEEYMVNTFIVMQRKLGTAGQKL 1261

  Fly   322 AGTTALIAIVQ------GS-KLIVANVGDSRGVMYDWRGIAIPLSFDHKPQQVRERKRIHDAGGF 379
            .|...|..|..      || .|..||||..:.|:.. .|..:|||..:......|.|||......
Human  1262 GGAAVLCHIKHDPVDPGGSFTLTSANVGKCQTVLCR-NGKPLPLSRSYIMSCEEELKRIKQHKAI 1325

  Fly   380 IAFRGVWRVAGVLATSRALGDYPLKDKNLVIATPDILTFELNDHKPHFLILASDGLWDTFSNEEA 444
            |...|  :|.||..::|.|| |.....: |:..|.:.:..|.. :..|.||.|.||||:.|.|||
Human  1326 ITEDG--KVNGVTESTRILG-YTFLHPS-VVPRPHVQSVLLTP-QDEFFILGSKGLWDSLSVEEA 1385

  Fly   445 CTFALEHLKEPDFGAKSLAMESYKRGSVDNITVLVI---VFKNDVYKIGSSAGKAGEESLKVPAK 506
            .. |:.::.:....||.|...:...|..|:|:.:|:   |.::.......|||.|      ||..
Human  1386 VE-AVRNVPDALAAAKKLCTLAQSYGCHDSISAVVVQLSVTEDSFCCCELSAGGA------VPPP 1443

  Fly   507 SQPVAPAVV 515
            |..:.|..|
Human  1444 SPGIFPPSV 1452

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.