DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7115 and Ppm1b

DIOPT Version :9

Sequence 1:	NP_001260216.1	Gene:	CG7115 / 34069	FlyBaseID:	FBgn0027515	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001152968.1	Gene:	Ppm1b / 19043	MGIID:	101841	Length:	477	Species:	Mus musculus

Alignment Length:	418	Identity:	101/418 - (24%)
Similarity:	156/418 - (37%)	Gaps:	157/418 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 QSWEEMKQQSSAFAVLGRRPRMEDRFIIEENINNNTGISFFAVFDGHGGEFAADFAKDVLVKNIY 166
            |.| .::.:.:..||:|          |...::|   .|||||:|||.|...|::....|::
Mouse    30 QGW-RVEMEDAHTAVVG----------IPHGLDN---WSFFAVYDGHAGSRVANYCSTHLLE--- 77

  Fly   167 NKIIEMSKLLKTEGNSGDYDKSPYLARKQSRKDANKENTEPTAGVMRKDSLRKAHSTTADCSAIK 231
                                                                  |.||
Mouse    78 ------------------------------------------------------HITT------- 81

  Fly   232 QKTTEASIADIYTVQLNSAMRASGNLGAAKDSFLNNNNNGQNGAANAPPPNYEAKCYIEHGRINF 296
                            |...||:...|:|.:                  |:.|:   ::.| |..
Mouse    82 ----------------NEDFRAADKSGSALE------------------PSVES---VKTG-IRT 108

  Fly   297 GKLITDEIMSADYKLVEQAKRATNIAGTTALIAIVQGSKLIVANVGDSRGVMYDWRGIAIPLSFD 361
            |.|..||.|    :.....:...:.:|:||:..:|..:.:...|.||||.|:.. .|.....:.|
Mouse   109 GFLKIDEYM----RNFSDLRNGMDRSGSTAVGVMVSPTHMYFINCGDSRAVLCR-NGQVCFSTQD 168

  Fly   362 HKPQQVRERKRIHDAGGFIAFRGVWRVAGVLATSRALGDYPLK-------DKNLVIATPDILTFE 419
            |||....|::||.:|||.:.   :.||.|.||.|||||||..|       .:.||...|::  :|
Mouse   169 HKPCNPVEKERIQNAGGSVM---IQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEV--YE 228

  Fly   420 L-NDHKPHFLILASDGLWDTFSNEEACTFALEHLKEPDFGAKSLAMES---------YKRGSVDN 474
            : ...:..|::||.||:||..||||.|.|....|:..|      .:|:         ..:||.||
Mouse   229 IVRAEEDEFVVLACDGIWDVMSNEELCEFVKSRLEVSD------DLENVCNWVVDTCLHKGSRDN 287

  Fly   475 ITVLVIVFKNDVYKIGSSAGKAGEESLK 502
            ::|:::.|.|        |.|..||::|
Mouse   288 MSVVLVCFSN--------APKVSEEAVK 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7115	NP_001260216.1	PP2Cc	111..482	CDD:238083	92/387 (24%)
Ppm1b	NP_001152968.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		PP2Cc	23..295	CDD:238083	94/396 (24%)
		PP2C_C	289..365	CDD:369544	8/27 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810