Protein Alignment CG7115 and PPM1L

DIOPT Version :9

• Sequence 1: NP_001260216.1
• Gene: CG7115 / 34069
• FlyBaseID: FBgn0027515
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_640338.2
• Gene: PPM1L / 151742
• HGNCID: 16381
• Length: 360
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 156/460 - (33%)
• Similarity: 221/460 - (48%)
• Gaps: 125/460 - (27%)

  Fly    35 LAYIWKLCRLYVLRPEVIF--C-GLILFVLLLYLQAVDVWSRSILGRIQATLGRQKAVKMMELSA 96
            |:.:.::.|.::||||.:|  | .|.|:....:...|....:|....::...|  |..::|:...
Human     9 LSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKG--KVAEIMQNDR 71

  Fly    97 SAG-------DHQSWEEMKQQSSAFAVLGRRPRMEDRFIIEENINNNTGISFFAVFDGHGGEFAA 154
            ..|       ..::||......:.:::.|||..|||||.:..::.|.|..|.|.:|||||||.||
Human    72 LGGLDVLEAEFSKTWEFKNHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAA 136

  Fly   155 DFAKDVLVKNIYNKIIEMSKLLKTEGNSGDYDKSPYLARKQSRKDANKENTEPTAGVMRKDSLRK 219
            ::.|..|.:                            |.||..:|..|:.
Human   137 EYVKSRLPE----------------------------ALKQHLQDYEKDK--------------- 158

  Fly   220 AHSTTADCSAIKQKTTEASIADIYTVQLNSAMRASGNLGAAKDSFLNNNNNGQNGAANAPPPNYE 284
                                                                             
Human   159 ----------------------------------------------------------------- 158

  Fly   285 AKCYIEHGRINFGKLITDEIMSADYKLVEQAKRATNIAGTTALIAIVQGSKLIVANVGDSRGVMY 349
                 |:..:::..::..:|:|.|.:::|:...:.:.||||.|||::....|.||||||||||:.
Human   159 -----ENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLC 218

  Fly   350 DWRGIAIPLSFDHKPQQVRERKRIHDAGGFIAFRGVWRVAGVLATSRALGDYPLKDKNLVIATPD 414
            |..|.|||||.||||.|::|||||..|||||:|.|.|||.|:||.||:|||||||:.|:||..||
Human   219 DKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPD 283

  Fly   415 ILTFELNDHKPHFLILASDGLWDTFSNEEACTFALEHLKEPDFGAKSLAMESYKRGSVDNITVLV 479
            ||||:|:..:|.|:|||||||||.||||||..|..|.|.||.|||||:.::|:.||..|||||:|
Human   284 ILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLDEPHFGAKSIVLQSFYRGCPDNITVMV 348

  Fly   480 IVFKN 484
            :.|:|
Human   349 VKFRN 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7115	NP_001260216.1	PP2Cc	111..482	CDD:238083	136/370 (37%)
PPM1L	NP_640338.2	PP2Cc	93..351	CDD:238083	136/370 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147388
Domainoid	1	1.000	207	1.000	Domainoid score	I2903
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H33158
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2850
Isobase	1	0.950	-	0	Normalized mean entropy	S2500
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1044139at2759
OrthoFinder	1	1.000	-	-		FOG0005078
OrthoInspector	1	1.000	-	-		oto89515
orthoMCL	1	0.900	-	-		OOG6_105716
Panther	1	1.100	-	-	LDO	PTHR13832
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6413
SonicParanoid	1	1.000	-	-		X119
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.740