DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7115 and Ppm1g

DIOPT Version :9

Sequence 1:	NP_001260216.1	Gene:	CG7115 / 34069	FlyBaseID:	FBgn0027515	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_032040.1	Gene:	Ppm1g / 14208	MGIID:	106065	Length:	542	Species:	Mus musculus

Alignment Length:	514	Identity:	128/514 - (24%)
Similarity:	205/514 - (39%)	Gaps:	148/514 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 AVLGRRPRMEDRFIIEENINNNTGISFFAVFDGHGGE----FAADFAKDVLVKNIYNKIIEMSKL 175
            |:.|.|..|||.......::|.|  :.|:|:||||||    :.|.:..|         ||:..|.
Mouse    31 AMQGWRVSMEDAHNCIPELDNET--AMFSVYDGHGGEEVALYCAKYLPD---------IIKDQKA 84

  Fly   176 LKTEGNSGDYDKSPYLA--RKQSRKDANKENTE----PTAGVMRKDSLRKAHSTTADCSAIKQKT 234
            .| ||......:..:||  .|.:.::..||..:    ||.....||.:........:.:|:..:.
Mouse    85 YK-EGKLQKALQDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDDKDKVADEDDVDNEEAALLHEE 148

  Fly   235 TEASIADIYTVQLNSAMR----ASGNLGAAKDSFLNNNNNGQNGAANAPPPNYE---------AK 286
            ...:|.::.|....:..:    ....:|...:.    ...|.||.|....|:.|         ||
Mouse   149 ATMTIEELLTRYGQNCQKVPPHTKSGIGTGDEP----GPQGLNGEAGPEDPSRETPSQENGPTAK 209

  Fly   287 CYI------EHG----------------------------RINFGKLITDEIMSADYKLVEQ--- 314
            .:.      |||                            |:...|...|....:|....|:
Mouse   210 GHTGFSSNSEHGTEAGQISEPGTATGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEVEEEEDDS 274

  Fly   315 -----------AKRATN-------------------------------IAGTTALIAIVQGSKLI 337
                       ::.|.|                               .:||||::|:::|.:||
Mouse   275 EECSEDEDGYSSEEAENEEDEDDTEEAEEDDDEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLI 339

  Fly   338 VANVGDSRGVMYDWRGIAIPLSFDHKPQQVRERKRIHDAGGFIAFRGVWRVAGVLATSRALGDYP 402
            |||.||||.|:.: .|.|:.:|:||||:...|..||.:|||.:...|  ||.|.|..|||:||:.
Mouse   340 VANAGDSRCVVSE-AGKALDMSYDHKPEDEVELARIKNAGGKVTMDG--RVNGGLNLSRAIGDHF 401

  Fly   403 LK-DKNL------VIATPDILTFEL-NDHKPHFLILASDGLWDTFSNEEACTFALEHLKEPDFGA 459
            .| :|||      :.|.|||....| :||:  |:::|.||:|:..|::|...|....:.:.|...
Mouse   402 YKRNKNLPPQEQMISALPDIKVLTLTDDHE--FMVIACDGIWNVMSSQEVVDFIQSKISQRDENG 464

  Fly   460 --------------KSLAMESYKRGS-VDNITVLVIVFK-NDVYKIGSSAGKAG-EESL 501
                          :.||.::...|: .||:|.::|.|| .:..::.:.:||.. ||:|
Mouse   465 ELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTVELQAESGKRKLEEAL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7115	NP_001260216.1	PP2Cc	111..482	CDD:238083	121/491 (25%)
Ppm1g	NP_032040.1	PP2Cc	25..>110	CDD:214625	27/90 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	117..136		4/18 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	164..325		19/164 (12%)
		PP2Cc	<321..502	CDD:238083	66/185 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	513..542		5/11 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810