DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7115 and phlpp1

DIOPT Version :9

Sequence 1:	NP_001260216.1	Gene:	CG7115 / 34069	FlyBaseID:	FBgn0027515	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	XP_009294739.3	Gene:	phlpp1 / 100331906	ZFINID:	ZDB-GENE-131127-271	Length:	1483	Species:	Danio rerio

Alignment Length:	282	Identity:	69/282 - (24%)
Similarity:	106/282 - (37%)	Gaps:	57/282 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 AHSTTADCSAIKQKTTEASIADIYTVQLNSAMRASGNLGAAKDSFLNNNNNGQNGAANAPPPNYE 284
            :|..| :.|.:|.|...|:::      :||   ..|:..|....|        :|..|...| |.
Zfish   977 SHGYT-EASGVKNKLCVAALS------VNS---FCGSREALYGVF--------DGDRNVEVP-YL 1022

  Fly   285 AKCYIEHGRINFGKLITDEI----MSADYK----LVEQAKRAT---NIAGTTALIAIVQGS---- 334
            .:|       ....::.:|:    ...||.    ||.|.|..|   .:.|:..|..|....
Zfish  1023 LQC-------TMNDILAEELHRTKSEEDYMTNTFLVMQRKLGTAGQKLGGSAVLCHIRHDPTDPG 1080

  Fly   335 ---KLIVANVGDSRGVMYDWRGIAIPLSFDHKPQQVRERKRIHDAGGFIAFRGVWRVAGVLATSR 396
               .|..||||..:.|:.. .|.|:|||..|......|..||......|....  :|.||..::|
Zfish  1081 GCFTLTAANVGKCQAVLCR-DGKALPLSLLHNISIPEEYSRIRQHKAIITEDN--KVNGVTDSTR 1142

  Fly   397 ALGD---YPLKDKNLVIATPDILTFELNDHKPHFLILASDGLWDTFSNEEACTFALEHLKEPDFG 458
            .:|.   ||     .|:..|.:.|..|.. :..|.||.|.||::.....||.. |:..:.:....
Zfish  1143 IMGYSFLYP-----AVLPRPYVTTLPLTP-RDEFFILGSRGLFEALEPSEAVE-AVRKVPDALAA 1200

  Fly   459 AKSLAMESYKRGSVDNITVLVI 480
            ||.|...:...|..|:::.:|:
Zfish  1201 AKKLCTLAQSYGCTDSLSAVVV 1222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7115	NP_001260216.1	PP2Cc	111..482	CDD:238083	69/282 (24%)
phlpp1	XP_009294739.3	PH-like	343..439	CDD:327399
		LRR_8	446..505	CDD:316378
		leucine-rich repeat	470..494	CDD:275380
		LRR_8	493..551	CDD:316378
		leucine-rich repeat	495..517	CDD:275380
		leucine-rich repeat	518..540	CDD:275380
		leucine-rich repeat	541..563	CDD:275380
		leucine-rich repeat	564..586	CDD:275380
		NEL	569..>860	CDD:330839
		leucine-rich repeat	587..608	CDD:275380
		leucine-rich repeat	610..633	CDD:275380
		leucine-rich repeat	634..674	CDD:275380
		leucine-rich repeat	675..696	CDD:275380
		leucine-rich repeat	697..719	CDD:275380
		leucine-rich repeat	720..742	CDD:275380
		leucine-rich repeat	743..764	CDD:275380
		leucine-rich repeat	766..788	CDD:275380
		leucine-rich repeat	789..812	CDD:275380
		leucine-rich repeat	815..838	CDD:275380
		leucine-rich repeat	839..859	CDD:275380
		PP2Cc	970..1222	CDD:214625	68/280 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910