Protein Alignment LanB1 and TMEFF1

DIOPT Version :10

• Sequence 1: NP_476618.1
• Gene: LanB1 / 34068
• FlyBaseID: FBgn0261800
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: NP_003683.2
• Gene: TMEFF1 / 8577
• HGNCID: 11866
• Length: 380
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 78/325 - (24%)
• Similarity: 107/325 - (32%)
• Gaps: 120/325 - (36%)

  Fly   980 GNPDNGGTC-----SKCECSN-NVDLYDTGNCDRQTGACLKCLYQTTGDHCELCKDGFFGDALQQ 1038
            |...:||.|     ....||. ||...|...||..:     |.|.      .:||:.  ||.|:.
Human    46 GGGGSGGDCPGGKGKSINCSELNVRESDVRVCDESS-----CKYG------GVCKED--GDGLKC 97

  Fly  1039 NCQ-QCECDFL---GTNNTIAHCDRFTGQCPCLPNVQGVRCDQCAENHWK----IASGEGCESCN 1095
            .|| ||..:::   |:|.     |.:..:|       .:|...|  .|.|    ||.|. |.|.|
Human    98 ACQFQCHTNYIPVCGSNG-----DTYQNEC-------FLRRAAC--KHQKEITVIARGP-CYSDN 147

  Fly  1096 CDPIGALHEQCNSYTGQCQCKPGFGGRACNQCQAHYWGNPNEKCQPC----ECDQFGAADFQCDR 1156
            ....|...|:            |.|      .:.|   ..:.||.||    |||:        |.
Human   148 GSGSGEGEEE------------GSG------AEVH---RKHSKCGPCKYKAECDE--------DA 183

  Fly  1157 ETGNCVCHEGIGGYKCNECARGYIGQFPHCSPCGECFNNWDLILSALEDATTATILRAKEIKQVG 1221
            |...|||:....||..|          |.|:..|..:||            ...:..|..|||
Human   184 ENVGCVCNIDCSGYSFN----------PVCASDGSSYNN------------PCFVREASCIKQ-- 224

  Fly  1222 ATGAYTSEFSELDKKLQHIRNLLQNTSVSLVDIEKLDYETQSLRDQLQASHGRLSETEQNLDDIY 1286
                     .::|  ::|:.:.......||  :.|.|...|...|...||..|        :|:|
Human   225 ---------EQID--IRHLGHCTDTDDTSL--LGKKDDGLQYRPDVKDASDQR--------EDVY 268

  Fly  1287  1286
            Human   269  268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LanB1	NP_476618.1	Laminin_N	54..286	CDD:459653
		EGF_Lam	287..343	CDD:238012
		Laminin_EGF	355..415	CDD:395007
		Laminin_EGF	418..475	CDD:395007
		EGF_Lam	477..526	CDD:238012
		EGF_Lam	529..567	CDD:214543
		EGF_Lam	789..834	CDD:214543
		Laminin_EGF	837..885	CDD:395007
		Laminin_EGF	883..930	CDD:395007
		Laminin_EGF	933..988	CDD:395007	3/7 (43%)
		Laminin_EGF	991..1035	CDD:395007	12/44 (27%)
		Laminin_EGF	1043..1091	CDD:395007	12/54 (22%)
		Laminin_EGF	1094..1142	CDD:395007	8/47 (17%)
		Laminin_EGF	1142..1190	CDD:395007	14/51 (27%)
		Mplasa_alph_rch	1228..>1771	CDD:275316	13/59 (22%)
		cc_DmLAMB1-like_C	1717..1786	CDD:411973
TMEFF1	NP_003683.2	KAZAL	99..143	CDD:197624	15/58 (26%)
		KAZAL	189..235	CDD:197624	16/80 (20%)
		PHA02887	<275..311	CDD:165214
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	359..380