DRSC/TRiP Functional Genomics Resources

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Protein Alignment LanB1 and si:dkey-220k22.1

DIOPT Version :9

Sequence 1:NP_476618.1 Gene:LanB1 / 34068 FlyBaseID:FBgn0261800 Length:1788 Species:Drosophila melanogaster
Sequence 2:XP_001336203.3 Gene:si:dkey-220k22.1 / 795920 ZFINID:ZDB-GENE-060526-255 Length:574 Species:Danio rerio


Alignment Length:414 Identity:120/414 - (28%)
Similarity:175/414 - (42%) Gaps:58/414 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   669 ATSSETRIPFSLPDRSRQVVALNEVCLEAGKVYKFRIY----------FERKRHDVDSPTATILV 723
            :.|.|.|:|.::.|.:.:...:.....|..:..:|..:          |...|:     |..:..
Zfish    26 SASDERRLPRAVLDETLEATTIPNHLQEDDRDSRFSPFTPAMTISNRDFRTTRN-----TNQVQS 85

  Fly   724 DSLTLIPRIDVTPIFQGSVLADIRKKDYE------------------KYNCKSSLYDMNYKSDPK 770
            |.||.......|||....::........|                  |....|.:.|....:.|.
Zfish    86 DWLTTTTTTTTTPITTAELMTKTMNPTSEGSKVKENSTLSTTLNTTAKPTSSSPINDTKNTTPPA 150

  Fly   771 CQNLDNILS--------VFVHDGASMCNCNPTGSLSK-VCESNGGYCQCKPNVVGRQCDQCAPGT 826
            ....::..:        |...:....|||:..||:.. .|:|....|.|.....|::||:|....
Zfish   151 LDTSNSTRTVKSTSNPPVVTTEKGMQCNCSTEGSVDPYTCDSVTSQCVCIIGYTGQRCDECEDEY 215

  Fly   827 YGFGPEGCKACDCNSIGSKDKYCDLITGQCQCVPNTYGRECNQCQPGYWNFPE--CRVCQCNGHA 889
            :..|..||:.|||:|.|:....|: .:|.|.|....:|.:|:.|.||:.||..  |:.||||.|:
Zfish   216 FTNGTNGCQPCDCHSYGAVSGLCN-SSGMCNCKMGVHGDKCDDCLPGFMNFSSTGCQTCQCNNHS 279

  Fly   890 ATCDPIQGTCIDCQDSTTGYSCDSCLDGYYGNPLFGSEI--GCRPCRCPETVASGLAHADGCSLD 952
            :.|.|..|.|::||.:|.|.||:.|...:|..|  ||.:  .|.||.|....::|     .|.||
Zfish   280 SYCHPQSGICMNCQGNTEGRSCEKCKYNFYRRP--GSPVTEPCIPCPCSSVTSTG-----SCKLD 337

  Fly   953 TRNNNMLCHCQEGYSGSRCEICADNFFGNPDNGGTCSKCECSNNVD-LYDTGNCDRQTGACLKCL 1016
            :|.......|:..|.|..||.|:|.|: |.|:  .|..|.||.|.| ......|...||.||.|:
Zfish   338 SRGQPYCVQCKPEYQGPNCEQCSDGFY-NADS--ICLPCNCSGNGDPRLSPRICHPDTGYCLSCI 399

  Fly  1017 YQTTGDHCELCKDGFFGDALQQNC 1040
            ..:||.|||.|.|||.||.|.:||
Zfish   400 NNSTGPHCERCADGFTGDPLARNC 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LanB1NP_476618.1 Laminin_N 63..286 CDD:278484
EGF_Lam 287..343 CDD:238012
Laminin_EGF 355..415 CDD:278482
Laminin_EGF 418..475 CDD:278482
EGF_Lam 477..526 CDD:238012
EGF_Lam 529..567 CDD:214543
EGF_Lam 789..834 CDD:214543 14/45 (31%)
Laminin_EGF 837..885 CDD:278482 18/49 (37%)
Laminin_EGF 883..930 CDD:278482 20/48 (42%)
Laminin_EGF 933..988 CDD:278482 17/54 (31%)
Laminin_EGF 991..1043 CDD:278482 25/51 (49%)
Laminin_EGF 1043..1091 CDD:278482
Laminin_EGF 1094..1142 CDD:278482
Laminin_EGF 1142..1190 CDD:278482
COG6 1212..>1398 CDD:303003
TelA 1439..1782 CDD:226371
ApoLp-III_like 1545..1702 CDD:304399
si:dkey-220k22.1XP_001336203.3 EGF_Lam 177..223 CDD:214543 14/45 (31%)
Laminin_EGF 226..273 CDD:278482 17/47 (36%)
EGF_Lam 273..315 CDD:238012 19/43 (44%)
EGF_Lam 322..373 CDD:238012 19/58 (33%)
EGF_Lam 372..422 CDD:238012 23/49 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0994
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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