DRSC/TRiP Functional Genomics Resources

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Protein Alignment LanB1 and MEGF9

DIOPT Version :9

Sequence 1:NP_476618.1 Gene:LanB1 / 34068 FlyBaseID:FBgn0261800 Length:1788 Species:Drosophila melanogaster
Sequence 2:NP_001073966.2 Gene:MEGF9 / 1955 HGNCID:3234 Length:602 Species:Homo sapiens


Alignment Length:259 Identity:91/259 - (35%)
Similarity:138/259 - (53%) Gaps:18/259 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   788 MCNCNPTGSLS-KVCESNGGYCQCKPNVVGRQCDQCAPGTYGFGPEG-CKACDCNSIGSKDKYCD 850
            :|||:..|||: ..|....|.|:|:|...|..|:.|..|.|.....| |:.|||:..|:....|:
Human   203 VCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCN 267

  Fly   851 LITGQCQCVPNTYGRECNQCQPGYWNFPE--CRVCQCNGHAATCDPIQGTCIDCQDSTTGYSCDS 913
             .:|:|||.....|..|::||.||:.|.:  |..||||..:|:||.:.|.|::||:::.|..|:.
Human   268 -SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEE 331

  Fly   914 CLDGYYGNPLFGSEIGCRPCRCPETVASGLAHADGCSLDTRNNNMLC-HCQEGYSGSRCEICADN 977
            |.:|:|.:|....|  |..|.|....::|     .||:.:......| .|::||.|..|..|.:.
Human   332 CKEGFYQSPDATKE--CLRCPCSAVTSTG-----SCSIKSSELEPECDQCKDGYIGPNCNKCENG 389

  Fly   978 FFGNPDNGGTCSKCECSNNVDLYDTGN-CDRQTGACLKCLYQTTGDHCELCKDGFFGDALQQNC 1040
            :: |.|:  .|.||:|..:||...|.. |..::|.|:.||:.|||..||.|.:|:..| |:.||
Human   390 YY-NFDS--ICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEGYVHD-LEGNC 449

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LanB1NP_476618.1 Laminin_N 63..286 CDD:278484
EGF_Lam 287..343 CDD:238012
Laminin_EGF 355..415 CDD:278482
Laminin_EGF 418..475 CDD:278482
EGF_Lam 477..526 CDD:238012
EGF_Lam 529..567 CDD:214543
EGF_Lam 789..834 CDD:214543 17/46 (37%)
Laminin_EGF 837..885 CDD:278482 18/49 (37%)
Laminin_EGF 883..930 CDD:278482 18/46 (39%)
Laminin_EGF 933..988 CDD:278482 14/55 (25%)
Laminin_EGF 991..1043 CDD:278482 21/51 (41%)
Laminin_EGF 1043..1091 CDD:278482
Laminin_EGF 1094..1142 CDD:278482
Laminin_EGF 1142..1190 CDD:278482
COG6 1212..>1398 CDD:303003
TelA 1439..1782 CDD:226371
ApoLp-III_like 1545..1702 CDD:304399
MEGF9NP_001073966.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 38..199
EGF_Lam 204..252 CDD:238012 17/47 (36%)
Laminin_EGF 254..301 CDD:278482 17/47 (36%)
EGF_Lam 300..346 CDD:238012 18/47 (38%)
EGF_Lam <373..401 CDD:238012 10/30 (33%)
Laminin_EGF 400..>441 CDD:278482 16/40 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0994
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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