Protein Alignment LanB1 and lama3

DIOPT Version :10

• Sequence 1: NP_476618.1
• Gene: LanB1 / 34068
• FlyBaseID: FBgn0261800
• Length: 1788
• Species: Drosophila melanogaster
• Sequence 2: XP_005161783.1
• Gene: lama3 / 101882184
• ZFINID: ZDB-GENE-050208-475
• Length: 1711
• Species: Danio rerio
• Alignment Length: 905
• Identity: 199/905 - (21%)
• Similarity: 311/905 - (34%)
• Gaps: 286/905 - (31%)

  Fly   962 CQEGYSGSRCEICADNFFGNPDNGGTCSKCECSNNVDLYDTGNCDRQTGACLKCLYQTTGDHCEL 1026
            |..||...|         ..|.. |.|..|.|:..     :|:||..||.||.|.:.|.|||||.
Zfish    77 CDRGYYRER---------SGPYK-GRCVPCNCNGL-----SGDCDPHTGKCLNCQFNTAGDHCER 126

  Fly  1027 CKDGFFGDALQQNCQQCECDFLGTNNTIAHCDRFTGQCPCLPNVQGVRCDQCAENHWKIASGEGC 1091
            |.:|::|.|:.:.|:.|.|.......:.|        ..||                    |.|.
Zfish   127 CMEGYYGSAILRTCRMCPCPLTDPAKSFA--------VGCL--------------------GVGD 163

  Fly  1092 ESCNCDPIGALHEQCNSYTGQCQCKPGFGGRACNQCQAHYWGNP---NEKCQPCECDQFGAADFQ 1153
            |.                  :|.||||:.|..|.:|...|:|:|   ...||||:|:.    .:.
Zfish   164 EF------------------ECLCKPGYSGVRCERCALGYYGSPLAERGSCQPCDCEH----GYV 206

  Fly  1154 CDRETGNCVCHEGIGGYKCNEC------------------ARGYIGQFPHCSPCGECFNNWDLIL 1200
            ||..||:|...:......|.:|                  || .|.|....||....:..    |
Zfish   207 CDPLTGDCYEADDPDTDNCFDCDICVVKLMDDLAAMDEEFAR-LIDQLGSFSPNATSYTG----L 266

  Fly  1201 SALEDATTATILRAKEIKQVGATGAYTSEFSELDKKLQHIRNLLQNT--------------SVSL 1251
            ..||||...|.:..::         ||....:|..|:..:.:.|||.              |.|.
Zfish   267 EKLEDAIADTKVLVQK---------YTESVFKLKPKISELESHLQNVKDDLTALNDKAIEMSCSA 322

  Fly  1252 VDIEKLDYETQSLRDQLQASHGRLSETEQNLDDIYNSLSLSGVELESLQNHSRLVQQLSKELKEN 1316
            |.:.|...:|....|.|::....|.:..|...|..|..:.:|...|......:..|::.::::..
Zfish   323 VQLLKSIDQTYQRGDNLRSESVNLLQKIQEFLDKLNRSNNTGGNTEDATRMLKEAQRMLEKMRRQ 387

  Fly  1317 GIQLQESNIEGALNLTRHAYERVSNLSTLKD-----EANELASNTDRN--CKRVENLSN----KI 1370
            ..::|...:...|   |.|:..:|.:  |||     ..:.:|::..|.  ..|.|:|.:    .|
Zfish   388 TCRVQRELVNEEL---RKAHILLSLI--LKDLIFPLNGSLIAADRIRQDLMDRAEDLRDIQEAII 447

  Fly  1371 QAEADDLANN--NKLIEDYRAELTSLTSQIPEL-NNQVCGKPGDPCDSLCGGAGCGHCGGFLSCE 1432
            .|:.|.|..|  |||.|:   :|.::......| .||                  |:....|:..
Zfish   448 DAQLDVLKANGVNKLNEE---QLKNILKHFKALRKNQ------------------GNIIANLNMA 491

  Fly  1433 HGAKTHSEEALKVAKDAETAITSKKDQADQTIRALTQAKLNASEAYEKAKRGFEQSERYLNQTNA 1497
            .|       .||.|.|.:..:...|:........:..||.|.....|..             :||
Zfish   492 RG-------TLKDASDIQEMMDELKENMTHLAALIDGAKYNLEAKLELL-------------SNA 536

  Fly  1498 NIKLAENLFIALNNFQENKTASPSESKELAQKTLDLDLKLEPEEIETLGDQINRAVSSLKNVEAI 1562
            ..|            ||....:...::||.:..:||.:.:...:..|   .:::|:.::....||
Zfish   537 TAK------------QEVVRQAEEHAQELTKLAIDLQMVIMNIKNST---AVHKAIEAINAFTAI 586

  Fly  1563 IYRTKPDLDRVNNLQSIANATKEKADKILDSANSVVESLAAADESQGKAKDAIQQANS---NIEL 1624
                   ...:|..::.|...||.||..|.....        .:.|.||||.|..||:   |.:.
Zfish   587 -------TAAINEAEAAAKLAKEAADHALKDVQK--------QDLQNKAKDLINNANALLVNAKE 636

  Fly  1625 AGQDLEKIDE--ETYSAEAPANNTAQQVEKLAKKVQKL-------QNNIMKNDRD-----AKE-- 1673
            |...||.:.:  |.|      .|..||.|...|:::::       .|||.:.|.|     |||
Zfish   637 ASIQLEDVAQKCEAY------KNLIQQAEDKQKQLKQVMLDVLEKMNNIKRGDIDILINQAKEGA 695

  Fly  1674 ----------------ITKEAGSVKLEAMRARGEANNLQSATSATNQTLT----------DRASR 1712
                            |:::...|.:..     :..||.:.....|:|||          |:.:.
Zfish   696 AGVNATAADALTRMQNISEDLNKVNIST-----QDQNLYNLLDGVNKTLTELDQTFPSLIDKLND 755

  Fly  1713 SEN-------------ARERAKQLLQRA--------SKLTVDTNAKL-----KDLNDLQT 1746
            .||             :.||.|.|:::.        ..:....||.:     |||.|.:|
Zfish   756 VENQTEHLPGPTNLSSSIERIKVLIEQTRDAANRIRGPILFSGNAHIELRPPKDLEDFRT 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LanB1	NP_476618.1	Laminin_N	54..286	CDD:459653
		EGF_Lam	287..343	CDD:238012
		Laminin_EGF	355..415	CDD:395007
		Laminin_EGF	418..475	CDD:395007
		EGF_Lam	477..526	CDD:238012
		EGF_Lam	529..567	CDD:214543
		EGF_Lam	789..834	CDD:214543
		Laminin_EGF	837..885	CDD:395007
		Laminin_EGF	883..930	CDD:395007
		Laminin_EGF	933..988	CDD:395007	6/25 (24%)
		Laminin_EGF	991..1035	CDD:395007	19/43 (44%)
		Laminin_EGF	1043..1091	CDD:395007	6/47 (13%)
		Laminin_EGF	1094..1142	CDD:395007	13/50 (26%)
		Laminin_EGF	1142..1190	CDD:395007	15/65 (23%)
		Mplasa_alph_rch	1228..>1771	CDD:275316	126/618 (20%)
		cc_DmLAMB1-like_C	1717..1786	CDD:411973	11/43 (26%)
lama3	XP_005161783.1	EGF_Lam	95..141	CDD:238012	20/50 (40%)
		Laminin_EGF	143..196	CDD:395007	19/98 (19%)
		TNFRSF	167..231	CDD:473981	23/67 (34%)
		Laminin_I	268..495	CDD:310534	55/268 (21%)
		HEC1	<442..806	CDD:444066	89/445 (20%)
		Laminin_II	691..819	CDD:368703	25/130 (19%)
		Laminin_G_2	847..979	CDD:460494
		LamG	1009..1149	CDD:238058
		LamG	1197..1303	CDD:238058
		LamG	1384..1515	CDD:238058
		LamG	1540..1688	CDD:238058