Protein Alignment cdc14 and CDC14

DIOPT Version :9

• Sequence 1: NP_001285721.1
• Gene: cdc14 / 34067
• FlyBaseID: FBgn0031952
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_116684.3
• Gene: CDC14 / 850585
• SGDID: S000001924
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 633
• Identity: 179/633 - (28%)
• Similarity: 277/633 - (43%)
• Gaps: 132/633 - (20%)

  Fly    15 EMQEDRLYFVAFKKNIKPKNTVNTHYFSVDEEFIYENFYNDFGPLNICMLYRYCMKLNTKLNAKC 79
            |....|:|..|:  :..|::|....:|:|::...|.:|:.||||:||..|||:.:..:..||...
Yeast    12 EFLRGRVYLGAY--DYTPEDTDELVFFTVEDAIFYNSFHLDFGPMNIGHLYRFAVIFHEILNDPE 74

  Fly    80 HANKKIVHYTSMNPAKRLNAAYLIGSYAIIYLNKTPQEAYRPLVAGEIPAYTRFCDASYGPSNFK 144
            :|||.:|.|:|.:..:|.|||.::..|.|:....||.:..:||...: |.:..|.||.|..::|:
Yeast    75 NANKAVVFYSSASTRQRANAACMLCCYMILVQAWTPHQVLQPLAQVD-PPFMPFRDAGYSNADFE 138

  Fly   145 ISLLDCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIVPQKFIAFCGPHQKSKTLPNGY 209
            |::.|.:..|.:..:.|..:.:.|:.|.||.:|.||.||||.:.|. ||||..|.:..   |.||
Yeast   139 ITIQDVVYGVWRAKEKGLIDLHSFNLESYEKYEHVEFGDFNVLTPD-FIAFASPQEDH---PKGY 199

  Fly   210 ----PCHAPERY---FSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKK 267
                ..|..:.:   .::|.:|||..|:|||:.:|:...||:.|..|.||.|.||:.|..:|:|.
Yeast   200 LATKSSHLNQPFKSVLNFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVKN 264

  Fly   268 FLSICET---TKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQWM 329
            |:...||   ..|.|||||||||||||.||||:::..|||||.|.|.:||..|||.|:|.||.|:
Yeast   265 FVGAAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGMVVGPQQHWL 329

  Fly   330 ----EDKQSWLWSEGERMRRRTSLPILQHTYGINSLE----LKKKLASAAADSTEHVDLLLTRVK 386
                .|.:.|.::....::...::..|   |.:.|||    .||||..
Yeast   330 YLHQNDFREWKYTTRISLKPSEAIGGL---YPLISLEEYRLQKKKLKD----------------- 374

  Fly   387 GISQRVDTMHLNDQDNLDAACTDQTDEELSEQLRLERDERALYQSVEDPNCNNSDDNDTDTISAP 451
              .:||      .|:|::....|.|
Yeast   375 --DKRV------AQNNIEGELRDLT---------------------------------------- 391

  Fly   452 ADPPPTSSYTISTRRRKSPSGAN-------KPTVIATSLRRLVNPNANRSGLSTASGVYPTPELA 509
            ..||......:|.|....||.||       ...|..||..:   |...::|.:|...:
Yeast   392 MTPPSNGHGALSARNSSQPSTANNGSNSFKSSAVPQTSPGQ---PRKGQNGSNTIEDI------- 446

  Fly   510 SCTEKKLRKPSANVFEAARHTIASTVRMTQTALEKKQAQTQGDKLNQIKALRRHHSRSVNVNSNS 574
                ...|.|::       |.....|..:..:.::....|.|...:..|..|:.:..|   :::|
Yeast   447 ----NNNRNPTS-------HANRKVVIESNNSDDESMQDTNGTSNHYPKVSRKKNDIS---SASS 497

  Fly   575 SEQESNVRHTRARSQPFRNNNNGVGGNTAMAALKPTSSCLPTGTGTAA 622
            |..|.|        :|...|.|....:|.:..|.|.:..:.:|..|.:
Yeast   498 SRMEDN--------EPSATNINNAADDTILRQLLPKNRRVTSGRRTTS 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cdc14	NP_001285721.1	DSPn	19..156	CDD:291343	45/136 (33%)
		PTPc	217..331	CDD:304379	59/123 (48%)
		CDC14	<229..330	CDD:225297	55/107 (51%)
CDC14	NP_116684.3	DSPn	14..151	CDD:405373	45/139 (32%)
		CDC14_C	161..340	CDD:350349	81/182 (45%)
		PRK08581	403..>513	CDD:236304	28/141 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344095
Domainoid	1	1.000	81	1.000	Domainoid score	I2005
eggNOG	1	0.900	-	-		E2759_KOG1720
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1763
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001645
OrthoInspector	1	1.000	-	-		oto98994
orthoMCL	1	0.900	-	-		OOG6_100917
Panther	1	1.100	-	-	LDO	PTHR23339
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R450
SonicParanoid	1	1.000	-	-		X1202
TreeFam	1	0.960	-	-
	13	12.680