DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cdc14 and cdc14b

DIOPT Version :9

Sequence 1:	NP_001285721.1	Gene:	cdc14 / 34067	FlyBaseID:	FBgn0031952	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001096152.1	Gene:	cdc14b / 733733	XenbaseID:	XB-GENE-977314	Length:	362	Species:	Xenopus tropicalis

Alignment Length:	362	Identity:	187/362 - (51%)
Similarity:	239/362 - (66%)	Gaps:	26/362 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 MKLNTKLNAKCHANKKIVHYTSMNPAKRLNAAYLIGSYAIIYLNKTPQEAYRPLVAGEIPAYTRF 133
            ||||.|:.:.....|||||||..:..|:.|||:|:||:|||||||.|.|.||.|...: ..|..|
Frog     1 MKLNKKIKSFSLTKKKIVHYTCGDDKKQANAAFLVGSFAIIYLNKQPLELYRLLQTAK-TNYLPF 64

  Fly   134 CDASYGPSNFKISLLDCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIVPQKFIAFCGP 198
            .|||:|...|.::||||..||||.||..||:|..||.|||:::||.||||||||:|:||:||.||
Frog    65 RDASFGTCTFHLTLLDCFFAVHKALQYNFFDFKTFDVEEYQHYERAENGDFNWIIPEKFLAFSGP 129

  Fly   199 HQKSKTLPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDA 263
            ||||| :.:|||.||||.||.|||.:|:||:||||.|:|.|..|.:|.|:|.||||:||||||||
Frog   130 HQKSK-IESGYPHHAPEAYFPYFRKHNITTIIRLNKKMYEAKRFTDANFEHYDLFFVDGSTPSDA 193

  Fly   264 IMKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQW 328
            |::|||:|||..:|||||||||||||||:|||:|:||||..||.|.|||:|:||||||||.|||:
Frog   194 IVRKFLNICENAEGAIAVHCKAGLGRTGTLIGSYMMKHYRMTAAETIAWIRICRPGSVIGPQQQF 258

  Fly   329 MEDKQSWLWSEGERMRRRTSLPILQHTYGINSLELKKKLASAAADSTEHVDLLLTRVKGISQRVD 393
            |.:||..||:||:..|                    |||......:...|..:|:.|..||...|
Frog   259 MVEKQRSLWNEGDIYR--------------------KKLQEQENGNRCAVTFILSGVDDISISDD 303

  Fly   394 TMHLNDQDNLDAACTDQTDEEL----SEQLRLERDER 426
            ......::::.....|..||.:    .::||..:.:|
Frog   304 KGKACGKEDIGLYSEDDDDESIHVTQGDKLRALKCKR 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cdc14	NP_001285721.1	DSPn	19..156	CDD:291343	44/86 (51%)
		PTPc	217..331	CDD:304379	80/113 (71%)
		CDC14	<229..330	CDD:225297	71/100 (71%)
cdc14b	NP_001096152.1	DSPn	<1..88	CDD:317115	45/87 (52%)
cdc14b	NP_001096152.1	CDC14	111..282	CDD:225297	117/191 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	159	1.000	Domainoid score	I4033
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	484	1.000	Inparanoid score	I1415
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001645
OrthoInspector	1	1.000	-	-		otm47524
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1202
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960