DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cdc14 and ptpdc1b

DIOPT Version :9

Sequence 1:	NP_001285721.1	Gene:	cdc14 / 34067	FlyBaseID:	FBgn0031952	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	XP_009294876.1	Gene:	ptpdc1b / 570928	ZFINID:	ZDB-GENE-090312-138	Length:	658	Species:	Danio rerio

Alignment Length:	401	Identity:	90/401 - (22%)
Similarity:	157/401 - (39%)	Gaps:	91/401 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 TVIRLNAKVYHAS----------------SFENAGFDHKDLFFID---GSTPSDAIMKKFLSICE 273
            |:|.|.....|||                :|..||....:..:||   .|..|...|.|.:|..
Zfish    94 TIINLQCPGEHASCGNPLDPDSGFTYRPETFMEAGIYFYNFRWIDYGVASLTSILDMVKVMSFA- 157

  Fly   274 TTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQ--------QWME 330
            ..:|.:||||.|||||||.|:..|::.....||.:||..:|..||.|:....|        |::.
Zfish   158 IQEGKMAVHCHAGLGRTGVLLACYLLFTTQMTADQAILLIRNKRPNSIQTRGQLQCVRQFAQFLV 222

  Fly   331 DKQSWLWSEGERMRRRTSLP--ILQHTYGINSLELKK------------KLASAAADSTEHVDLL 381
            ..:: |::..|......:|.  :::..:.::.||.::            :|....|::.:.::..
Zfish   223 PLRN-LFANAEPRAPAVTLSQFLIRQKHILHGLEARQLRYMPKLVPLISRLLLDIAENRQVIEED 286

  Fly   382 LTRVKGISQRVD-TMHLNDQDNLDAACTDQTDEELSEQLRLERDERALYQSVEDPNCNNSDDNDT 445
            :..|..|:..|: |.:.|...:.:                  |:..|...::..|........:.
Zfish   287 IVEVPDITPVVEKTFNENSIHSFN------------------REMLANGMAMIKPRLPGLPKTNR 333

  Fly   446 DTISAPADPPPTSSYTISTRRR--KSPSGANKPTVIATSLRRLVNPNANRSG-LSTASGVYPTPE 507
            |..........:.||:.|..||  :|.:..:.|..:..|::  ::..:|:.| .|..|...|.|.
Zfish   334 DNSQPLYYVRKSLSYSDSDLRRLAESLNLPDNPLCVLASMQ--LSSMSNQLGAFSCVSQNSPAPP 396

  Fly   508 LASCTEKKLRKPSANVFEAARHTIASTVRMTQTALEKKQAQTQGDKLNQIKALRR---HHSRSVN 569
            |.:|....:...|:|::|                |:....||:|..|  :|..|:   ..|||:.
Zfish   397 LGACKGNPIYSSSSNLWE----------------LKTLMDQTEGSPL--LKNRRQSFLQRSRSLG 443

  Fly   570 VNSNSSEQESN 580
            |   |.||.:|
Zfish   444 V---SDEQNTN 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cdc14	NP_001285721.1	DSPn	19..156	CDD:291343
		PTPc	217..331	CDD:304379	40/129 (31%)
		CDC14	<229..330	CDD:225297	39/127 (31%)
ptpdc1b	XP_009294876.1	PTPc_motif	136..210	CDD:214649	29/74 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1720
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810