DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cdc14 and dusp23b

DIOPT Version :9

Sequence 1:	NP_001285721.1	Gene:	cdc14 / 34067	FlyBaseID:	FBgn0031952	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001002462.1	Gene:	dusp23b / 436735	ZFINID:	ZDB-GENE-040718-163	Length:	152	Species:	Danio rerio

Alignment Length:	158	Identity:	38/158 - (24%)
Similarity:	66/158 - (41%)	Gaps:	34/158 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 DFNWIVPQKFIAFCGPHQKSKTLPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGF 247
            :|:|:.|.|......|...:              ::.|..::.:..::.|.         |....
Zfish     8 NFSWVDPGKVAGLAMPRMTA--------------HYQYLLNSGIKHLVTLT---------ERKPP 49

  Fly   248 DH---KDLF-----FIDGSTPSDAIMKKFLSICETTKG---AIAVHCKAGLGRTGSLIGAYIMKH 301
            ||   .||.     ..|...|:...:.:||:|.|....   |:||||..|.||||:::..|::|.
Zfish    50 DHDTCPDLTLHHIKINDFCAPTFEQINRFLTIVEEANASGQAVAVHCLHGFGRTGTMLACYLVKS 114

  Fly   302 YGFTALEAIAWLRLCRPGSVIGHQQQWM 329
            ...:.::||..:|..|.||:...:|:.|
Zfish   115 RKISGIDAINEIRRIRRGSIETREQEQM 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cdc14	NP_001285721.1	DSPn	19..156	CDD:291343
		PTPc	217..331	CDD:304379	33/124 (27%)
		CDC14	<229..330	CDD:225297	32/112 (29%)
dusp23b	NP_001002462.1	PTPc	34..134	CDD:304379	29/108 (27%)
dusp23b	NP_001002462.1	CDC14	<61..146	CDD:225297	26/82 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1720
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810