DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cdc14 and dusp23a

DIOPT Version :9

Sequence 1:	NP_001285721.1	Gene:	cdc14 / 34067	FlyBaseID:	FBgn0031952	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001034709.1	Gene:	dusp23a / 323834	ZFINID:	ZDB-GENE-030131-2554	Length:	161	Species:	Danio rerio

Alignment Length:	163	Identity:	43/163 - (26%)
Similarity:	77/163 - (47%)	Gaps:	19/163 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 ENGDFNWIVPQKFIAFCGPHQKSKTLPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFEN 244
            |..:|:|:.|.|......|     |:.:         ::.|..|:.:..::.| .::...:..:.
Zfish     9 EPPNFSWVEPCKLAGLARP-----TMVH---------HYRYLLDHGIKHLVSL-LEIKPPNYEKC 58

  Fly   245 AGFDHKDLFFIDGSTPSDAIMKKFLSICE--TTKG-AIAVHCKAGLGRTGSLIGAYIMKHYGFTA 306
            .......:..:|.:.||.:.:.:||||.|  ..|| .:||||..|.||||:::..|::|....:.
Zfish    59 PELSLHQISIVDFTPPSRSQILQFLSIVEKANAKGEGVAVHCAHGHGRTGTMLACYLVKSRHLSG 123

  Fly   307 LEAIAWLRLCRPGSV-IGHQQQWMEDKQSWLWS 338
            .|||..:|..|.||| ...|:|.:.|..:::.|
Zfish   124 EEAIKEIRRLREGSVETKEQEQAVIDFHNYIHS 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cdc14	NP_001285721.1	DSPn	19..156	CDD:291343
		PTPc	217..331	CDD:304379	34/117 (29%)
		CDC14	<229..330	CDD:225297	32/104 (31%)
dusp23a	NP_001034709.1	PTPc	39..140	CDD:304379	30/101 (30%)
dusp23a	NP_001034709.1	CDC14	<65..151	CDD:225297	32/85 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1720
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810