Protein Alignment Cdc14 and Cdc14b

DIOPT Version :10

• Sequence 1: NP_609153.1
• Gene: Cdc14 / 34067
• FlyBaseID: FBgn0031952
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_036013890.1
• Gene: Cdc14b / 218294
• MGIID: 2441808
• Length: 530
• Species: Mus musculus
• Alignment Length: 517
• Identity: 219/517 - (42%)
• Similarity: 304/517 - (58%)
• Gaps: 88/517 - (17%)

  Fly    19 DRLYFVAFKKNIKPKNTVNTHYFSVDEEFIYENFYNDFGPLNICMLYRYCMKLNTKLNAKCHANK 83
            |||.|.....  :||:..|.||||:|.|..|||||.||||||:.|:||||.|:|.||.:.....|
Mouse    54 DRLCFAILYS--RPKSATNEHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITMLRK 116

  Fly    84 KIVHYTSMNPAKRLNAAYLIGSYAIIYLNKTPQEAYRPLVAGEIPAYTRFCDASYGPSNFKISLL 148
            ||:|:|..:..|:.|||:|:|.|.:|||.:||::|||.|:.|: .||..|.||:||..:|.|:||
Mouse   117 KIIHFTGTDQRKQANAAFLVGCYMVIYLGRTPEDAYRTLIFGD-TAYIPFRDAAYGSCSFYITLL 180

  Fly   149 DCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIVPQKFIAFCGPHQKSKTLPNGYPCHA 213
            ||.:||.|.:|.||||||.|:.:|||::|:.||||||||:|::|:||||||.:|: |.:||..|:
Mouse   181 DCFHAVKKAMQYGFFNFNSFNLDEYEHYEKAENGDFNWIIPERFLAFCGPHSRSR-LESGYHQHS 244

  Fly   214 PERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFLSICETTKGA 278
            ||.|..||:::||||:||||.::|.|..|.:|||||.||||.|||||:::|:::||.|||..|||
Mouse   245 PETYIPYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFPDGSTPAESIVQEFLDICENVKGA 309

  Fly   279 IAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQWMEDKQSWLWSEGERM 343
            |||||||||||||:|||.|:||||..||.|:|||||:||||||||.|||::..|||.||.||:..
Mouse   310 IAVHCKAGLGRTGTLIGCYLMKHYRMTAAESIAWLRICRPGSVIGPQQQFLVMKQSSLWLEGDYF 374

  Fly   344 RRRTSLPILQHTYGINSLELKKKLASAAADSTEHVDLLLTRVKGISQRVDTMHLNDQDNLDAACT 408
            |::                                  |..:..|..:...:.||:|.|:|.....
Mouse   375 RQK----------------------------------LRGQENGPLREAFSKHLSDADDLSLNGL 405

  Fly   409 DQTDEELSEQLRLERDERALYQSVEDPNCNNSDDNDT------DTISAPADPPPTSSYTISTRRR 467
            :..|.:..|..                    |||::.      |.:.|           :.:||:
Mouse   406 ENQDNQEPEPY--------------------SDDDEVSGMTQGDRLRA-----------LKSRRQ 439

  Fly   468 KSPSGANKPTVIATSLRRLVNPNANRSGLSTASGVYPTPELASCTEKKLRKPSA-NVFEAAR 528
            ...|......::.:|::....|..|.||   ::|:         |::..|..|. :.|::.|
Mouse   440 PKASAIPLTVILQSSVQSCKTPEPNLSG---SAGI---------TKRTTRSASGKSSFKSLR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc14	NP_609153.1	CDC14_N	12..158	CDD:350495	71/138 (51%)
		CDC14_C	167..341	CDD:350349	111/173 (64%)
Cdc14b	XP_036013890.1	CDC14_N	52..190	CDD:350495	71/138 (51%)
		CDC14_C	199..372	CDD:350349	111/173 (64%)