DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cdc14 and Ptpdc1

DIOPT Version :9

Sequence 1:	NP_001285721.1	Gene:	cdc14 / 34067	FlyBaseID:	FBgn0031952	Length:	1052	Species:	Drosophila melanogaster
Sequence 2:	NP_001288710.1	Gene:	Ptpdc1 / 218232	MGIID:	2145430	Length:	808	Species:	Mus musculus

Alignment Length:	168	Identity:	50/168 - (29%)
Similarity:	67/168 - (39%)	Gaps:	37/168 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 ERVENGDFNWIVPQKFIAFCGPHQKSKTLPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHAS- 240
            |:...|.::..|....:|...|   |..|...|      |....|....:.|:|.|.....|||
Mouse   136 EQAIKGVYSSWVTDNILAMARP---SSELLEKY------RIIEQFLGQGIKTIINLQRPGEHASC 191

  Fly   241 ---------------SFENAG-----FDHKDLFFIDGSTPSDAI--MKKFLSICETTKGAIAVHC 283
                           :|..||     |..||.    |.....||  |.|.::.. ..:|.:||||
Mouse   192 GSALEQESGFTYLPEAFMEAGIYFYNFGWKDY----GVASLTAILDMVKVMTFA-LQEGKVAVHC 251

  Fly   284 KAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSV 321
            .|||||||.||..|::.....||.:||.::|..||.|:
Mouse   252 HAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSI 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cdc14	NP_001285721.1	DSPn	19..156	CDD:291343
		PTPc	217..331	CDD:304379	41/128 (32%)
		CDC14	<229..330	CDD:225297	39/116 (34%)
Ptpdc1	NP_001288710.1	PTPc_motif	215..296	CDD:214649	31/80 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1720
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810