Protein Alignment cdc14 and cdc-14

DIOPT Version :9

• Sequence 1: NP_001285721.1
• Gene: cdc14 / 34067
• FlyBaseID: FBgn0031952
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001300510.1
• Gene: cdc-14 / 173945
• WormBaseID: WBGene00000383
• Length: 709
• Species: Caenorhabditis elegans
• Alignment Length: 926
• Identity: 272/926 - (29%)
• Similarity: 391/926 - (42%)
• Gaps: 295/926 - (31%)

  Fly    14 SEMQEDRLYFVAFKK----NIKPKNTVNTHYFSVDEEFIYENFYNDFGPLNICMLYRYCMKLNTK 74
            :|:..:||||..|..    :...|:...|.:.:::.:|.||.||.||||.|:.:|||.|:::...
 Worm    18 TELLPNRLYFGCFPNPDAIDKSDKSVKKTCFININNKFHYEPFYEDFGPWNLSVLYRLCVQVGKL 82

  Fly    75 LNAKCHANKKIVHY-----TSMNPAKRLNAAYLIGSYAIIYLNKTPQEAYRPLVAGEIPAYTRFC 134
            |..:...::::|.:     |......|:|.||::|:|.|||...:..:||..:.:||...:..|.
 Worm    83 LEVEEKRSRRVVLFCQDDGTGQYDKIRVNTAYVLGAYLIIYQGFSADDAYLKVSSGETVKFVGFR 147

  Fly   135 DASYGPSNFKISLLDCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIVPQKFIAFCGPH 199
            |||.|...:.:.|.|.|..:.|.|:.|:.:|:|||.||||::|||||||||||:|.|.::|||||
 Worm   148 DASMGSPQYLLHLHDVLRGIEKALKFGWLDFSDFDYEEYEFYERVENGDFNWIIPGKILSFCGPH 212

  Fly   200 QKSKTLPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAI 264
            .:|:. .||||.|||:.||.|||:|.|:|::|||||.|.||.|..|||||.||||||||||||.|
 Worm   213 NESRE-ENGYPYHAPDVYFDYFRENKVSTIVRLNAKNYDASKFTKAGFDHVDLFFIDGSTPSDEI 276

  Fly   265 MKKFLSICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQWM 329
            |.||:.:.:.|||.:||||||||||||:||..::||.||.||.|.:.|||:||||||||.||.::
 Worm   277 MLKFIKVVDNTKGGVAVHCKAGLGRTGTLIACWMMKEYGLTAGECMGWLRVCRPGSVIGPQQPYL 341

  Fly   330 EDKQSWLWSEGERMRRRTSLPILQHTYGINSLELKKKLASAAADSTEHVDLLLTRVKGISQRVDT 394
            .:||.:.||                                           |::..|:
 Worm   342 IEKQKFCWS-------------------------------------------LSQSNGV------ 357

  Fly   395 MHLNDQDNLDAACTDQTDEELSEQLRLERDERALYQSVEDPNCNNSDDNDTDTISAPADPPPTSS 459
             ||.           |..||       :|:.|.|...|:|.|....
 Worm   358 -HLT-----------QNKEE-------KRNVRRLVNQVDDINLGEE------------------- 384

  Fly   460 YTISTRRRKSPSGANKPTVIATSLRRLVNPNANRSGLSTASGVYPTPELASCTEKKLRKPSANVF 524
             .||.:.|::    .:|.:    |||.|..   ::|.|||. |...|              |...
 Worm   385 -RISPKSREN----TRPNI----LRRRVQV---QNGRSTAP-VTIAP--------------AGTS 422

  Fly   525 EAARHTIASTVRMTQTALEKKQAQTQGDKLNQIKALRRHHSRSVNVNSNSSEQ--ESNVRHTRAR 587
            |:.|.|..|.| :.:|||: .|.::|||:|.|:||..:|.|.:.:.||:||.:  :|:.......
 Worm   423 ESRRSTKPSRV-VDETALD-DQGRSQGDRLLQLKAKHQHESETTSPNSSSSRRFVKSSTPQMTVP 485

  Fly   588 SQPFRNNN----------NGVGGNTAMAALKPTSSCLPTGTGTAALLANNLNNNNDCGIGTSGSS 642
            ||.:.|.|          ||....|:...||.|    |.|
 Worm   486 SQAYLNRNREPIIVTPSKNGTSSGTSSRQLKTT----PNG------------------------- 521

  Fly   643 NNNHNNNNNNSNLSNSLNNYNNNNNTTNNIL------------ASSGSSRTRSLALYSKRMELKH 695
            |..:...|::.|.:::|....|.:...:|.|            ||..|..||.|:
 Worm   522 NVAYRTRNSSGNTTSTLTRTGNESYRFHNSLFYEPASAVFPSMASRRSETTRYLS---------- 576

  Fly   696 LRKAEQQQQQQVQQEQPLLPVEKQLLRQYATINESKIPVVSGGGGGAGSSATIPPTRGSAARTSH 760
                            |..|: |.:...|                   :..|.|
 Worm   577 ----------------PTTPI-KPMSPSY-------------------TDGTSP----------- 594

  Fly   761 HHMTLRGRSRIRYQRPNAGETAPAAAQTQPCTVATARYYRDVSAIPTIGVFGGGPGGSSSTSASF 825
                 |.::|:|.:.|                               ||         |:||..|
 Worm   595 -----RYKARLRSENP-------------------------------IG---------STTSTPF 614

  Fly   826 NIATRSASATLDLNSNP------LPKTTKLT-SLNNNPTTTPPPSSNPADTSRLSGRGSA----- 878
            ::..:....:|...|.|      :|.|:|.| ||.....:.|.|..:......|...|.:
 Worm   615 SLQPQITKCSLTAESKPPKRILSMPGTSKSTSSLKKIQVSRPRPYPSTGVRVELCANGKSYDIRP 679

  Fly   879 --ELQAIIEHGLVAGS 892
              |...|...||.|.:
 Worm   680 RKEAHVIPGAGLAANT 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cdc14	NP_001285721.1	DSPn	19..156	CDD:291343	45/145 (31%)
		PTPc	217..331	CDD:304379	75/113 (66%)
		CDC14	<229..330	CDD:225297	67/100 (67%)
cdc-14	NP_001300510.1	DSPn	21..170	CDD:317115	45/148 (30%)
		CDC14	192..347	CDD:225297	101/155 (65%)
		Herpes_BLLF1	<410..>656	CDD:330317	79/393 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159894
Domainoid	1	1.000	159	1.000	Domainoid score	I2505
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I1175
Isobase	1	0.950	-	0	Normalized mean entropy	S1763
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001645
OrthoInspector	1	1.000	-	-		oto20207
orthoMCL	1	0.900	-	-		OOG6_100917
Panther	1	1.100	-	-	LDO	PTHR23339
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R450
SonicParanoid	1	1.000	-	-		X1202
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.870