Protein Alignment cdc14 and cdc14a

DIOPT Version :9

• Sequence 1: NP_001285721.1
• Gene: cdc14 / 34067
• FlyBaseID: FBgn0031952
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_002934198.1
• Gene: cdc14a / 100490252
• XenbaseID: XB-GENE-960625
• Length: 575
• Species: Xenopus tropicalis
• Alignment Length: 692
• Identity: 267/692 - (38%)
• Similarity: 341/692 - (49%)
• Gaps: 191/692 - (27%)

  Fly    10 LVCASEMQEDRLYFVAFKKNIKPKNTVNTHYFSVDEEFIYENFYNDFGPLNICMLYRYCMKLNTK 74
            |:.|||:.:|||||...:.  |||:|:|||||..||||:|||||.||||||:..|||||.|||.|
 Frog     6 LISASELIKDRLYFATLRN--KPKSTLNTHYFCTDEEFVYENFYADFGPLNLAQLYRYCCKLNKK 68

  Fly    75 LNAKCHANKKIVHYTSMNPAKRLNAAYLIGSYAIIYLNKTPQEAYRPLVAGEIPAYTRFCDASYG 139
            |.:...:.||||||||....||.||.:||.:||||||.|:|:|.||.|::|....|..|.|||:|
 Frog    69 LKSFSLSRKKIVHYTSFEQRKRANAGFLISAYAIIYLKKSPEEVYRALLSGTNAQYLPFRDASFG 133

  Fly   140 PSNFKISLLDCLNAVHKGLQAGFFNFNDFDAEEYEYFERVENGDFNWIVPQKFIAFCGPHQKSKT 204
            ...:.:::||||..:.|.|..|||||.:|||:|||::|||||||||||||.||:||.|||.|||
 Frog   134 SCTYNLTILDCLQGIRKALYFGFFNFENFDADEYEHYERVENGDFNWIVPGKFLAFSGPHPKSK- 197

  Fly   205 LPNGYPCHAPERYFSYFRDNNVTTVIRLNAKVYHASSFENAGFDHKDLFFIDGSTPSDAIMKKFL 269
            :.||||.||||.||.|||.:|:..|||||.|:|.|..|.:|||||.||||:|||||||.|:::||
 Frog   198 IENGYPLHAPEAYFPYFRKHNIRAVIRLNKKIYDAKRFTDAGFDHYDLFFVDGSTPSDGIVRRFL 262

  Fly   270 SICETTKGAIAVHCKAGLGRTGSLIGAYIMKHYGFTALEAIAWLRLCRPGSVIGHQQQWMEDKQS 334
            ::||.|.|||||||||||||||:||..||||||..|..|||||:|:|||||:||.||.::|:||:
 Frog   263 NLCENTDGAIAVHCKAGLGRTGTLIACYIMKHYRLTHSEAIAWIRICRPGSIIGPQQHFLEEKQT 327

  Fly   335 WLWSEGERMRRRTSLPILQHTYGINSLELKKKLASAAADSTEHVDLLLTRVKGISQRVDTMHLND 399
            |||.:|:..|..                 :|::.|.        |..:||:           |.|
 Frog   328 WLWLQGDLHRSN-----------------QKQIQSE--------DQAVTRI-----------LTD 356

  Fly   400 QDNLDAACTDQTDEELSEQLRLERDERALYQSVEDPNCNNSDDNDTDTISAPADPPPTSSYTIST 464
            ...|..:      .:.|.....|||...           ||||.
 Frog   357 FGELSLS------GKFSSNNIYERDREI-----------NSDDE--------------------- 383

  Fly   465 RRRKSPSGANKPTVIATSLRRLVNPNANRSGLSTASGVYPTPELASCTEKKLRKPSANVFEAARH 529
                                                                             
 Frog   384 ----------------------------------------------------------------- 383

  Fly   530 TIASTVRMTQTALEKKQAQTQGDKLNQIKALRRHHSRSVNVNSNSSEQESNVRHTRARSQPFRNN 594
                        |:.....||||||..:|:  |.|.||  ..:.:...|....|||:.|||||
 Frog   384 ------------LDHSNGLTQGDKLRALKS--RRHPRS--ATTGALRLEDMKPHTRSTSQPFR-- 430

  Fly   595 NNGVGGNTAMAALKPTSSCLPTGTGTAA--LLANNLNNNNDCGIGTSGSSNNNHNNNNNNSNLSN 657
              .:..|:...::.|..|...|.:.:|.  .:|.:..:.|..|.|.|.           |...:.
 Frog   431 --VLASNSTQGSMSPLKSSRVTSSTSAVGRRVAQSPRSTNSKGGGFSA-----------NMRFAG 482

  Fly   658 SLNNYNN--------NNNTTNNILASS--------GSSRTRS 683
            ||.|.|:        ....||..::|.        ..||.||
 Frog   483 SLGNLNSALEEIESARRPYTNRAISSQAVPSNLYISHSRVRS 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cdc14	NP_001285721.1	DSPn	19..156	CDD:291343	76/136 (56%)
		PTPc	217..331	CDD:304379	76/113 (67%)
		CDC14	<229..330	CDD:225297	70/100 (70%)
cdc14a	XP_002934198.1	DSPn	11..150	CDD:373210	77/140 (55%)
		CDC14_C	161..334	CDD:350349	119/173 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	163	1.000	Domainoid score	I3927
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	484	1.000	Inparanoid score	I1415
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001645
OrthoInspector	1	1.000	-	-		otm47524
Panther	1	1.100	-	-	LDO	PTHR23339
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1202
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.150