DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment r2d2 and stau2

DIOPT Version :9

Sequence 1:	NP_001162903.1	Gene:	r2d2 / 34066	FlyBaseID:	FBgn0031951	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_001011376.2	Gene:	stau2 / 496843	XenbaseID:	XB-GENE-491508	Length:	706	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	64/315 - (20%)
Similarity:	112/315 - (35%)	Gaps:	106/315 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NKSAVSALQEFCARTQINLPTYSFIPGEDGG------YVCKVELLEIEALGNGRSKRDAKHLAAS 61
            |||.:|.:.|...:..::|   ||...::.|      :|.:|.:.|..|.|.|.||:.||..||:
Frog   305 NKSEISLVFEISLKRNLSL---SFEVIKESGPPHMKSFVTRVTVGEFTAEGEGNSKKLAKRRAAA 366

  Fly    62 NILRKIQLLPGIHGLMKDSTVGDLDEELTNLNRDMVKELRDYCVRREM--------------PLP 112
            .:|::::.||.:                     .::::.|.|..||..              |:.
Frog   367 AVLQELRKLPPL---------------------PVIEKPRIYIKRRPKNIIKASPEYGQGMNPIS 410

  Fly   113 CIEVVQQSGTPSAP--------------EFVACCSVASIVRYGKSDKKKDARQRAAIEMLALISS 163
            .:..:||:.....|              |||....|......|....||.|::.||..||
Frog   411 RLAQIQQAKKEKEPEYVLLSERGIQRRREFVMQVKVGEETATGTGPNKKTAKRNAAEAML----- 470

  Fly   164 NSDNLRPDQMQVASTSKLKVVDMEESMEELEALRRKKFTTYWELKEAGSVDHTGMRLCDRHNYFK 228
                     :|:...:...||         |...::.....|:.:.:|..|.|.
Frog   471 ---------LQLGYKASSPVV---------EKTGKRGENPDWDEQNSGIADQTS----------- 506

  Fly   229 NFYPTLKKEAIEAINSDEY---ESSKDK-----AMDVMSSLKITPKISEVESSSL 275
                  ..:.|..::.|.|   |:|::|     |:..:||.::....|...|:|:
Frog   507 ------TPKGILHLSPDVYQEMEASRNKTVPAPAISYLSSKEMNQASSSFFSTSV 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
r2d2	NP_001162903.1	DSRM	6..67	CDD:238007	19/66 (29%)
r2d2	NP_001162903.1	DSRM	95..158	CDD:238007	18/90 (20%)
stau2	NP_001011376.2	DSRM	91..152	CDD:214634
		DSRM	196..279	CDD:214634
		DSRM	309..>356	CDD:214634	12/49 (24%)
		DSRM	408..474	CDD:214634	17/79 (22%)
		Staufen_C	559..660	CDD:293091
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910