DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment r2d2 and stau1

DIOPT Version :9

Sequence 1:	NP_001162903.1	Gene:	r2d2 / 34066	FlyBaseID:	FBgn0031951	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	NP_991124.2	Gene:	stau1 / 334440	ZFINID:	ZDB-GENE-030131-6372	Length:	702	Species:	Danio rerio

Alignment Length:	190	Identity:	45/190 - (23%)
Similarity:	87/190 - (45%)	Gaps:	42/190 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 GNGRSKRDAKHLAASNILRKIQLLPGIHGL--MKDSTVGDLDEELTNLNRDMVKELRDYCVRREM 109
            |.||:::.|||.||:..::.:|..|.:..:  |.|....:      |||:..:.::.:..::|.|
Zfish   241 GKGRTRQAAKHDAAAKAIKYLQKEPILQQITEMTDEPAQE------NLNKSEISQVFEIALKRNM 299

  Fly   110 PLPCIEVVQQSGTPSAPEFVACCSVASIVRYGKSDKKKDARQRAAIEMLALISSNSDNLR--PDQ 172
            |:. .||::::|.|....||....|......|:...||.|:::|||.:|       :.||  |
Zfish   300 PVD-FEVLKEAGAPHMKSFVVRVVVGEFAGEGEGKSKKIAKKQAAIAVL-------EELRRLP-- 354

  Fly   173 MQVASTSKL---------KVVDMEESME------------ELEALRRKKFTTYWELKEAG 211
             |:.:|.|:         .::.::.|.|            :::..:::|...|..:.|.|
Zfish   355 -QLPATDKIPLRIKKKSKSIIKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYTLVTERG 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
r2d2	NP_001162903.1	DSRM	6..67	CDD:238007	8/19 (42%)
r2d2	NP_001162903.1	DSRM	95..158	CDD:238007	17/62 (27%)
stau1	NP_991124.2	DSRM	75..138	CDD:214634
		DSRM	287..350	CDD:214634	18/70 (26%)
		DSRM	387..453	CDD:238007	4/27 (15%)
		Staufen_C	551..660	CDD:293091
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810