Protein Alignment r2d2 and Stau2

DIOPT Version :10

• Sequence 1: NP_609152.1
• Gene: r2d2 / 34066
• FlyBaseID: FBgn0031951
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_079579.2
• Gene: Stau2 / 29819
• MGIID: 1352508
• Length: 570
• Species: Mus musculus
• Alignment Length: 186
• Identity: 46/186 - (24%)
• Similarity: 85/186 - (45%)
• Gaps: 26/186 - (13%)

  Fly    44 EALGNGRSKRDAKHLAASNILRKIQLLPGIHGLMKDSTVG-DLDEELTNLNRDMVKELRDYCVRR 107
            |..|.|::::.|:|.||...|:.:|..|......::...| ::|:: .:.|:..:..:.:..::|
Mouse   156 EFFGEGKTRQAARHNAAMKALQALQNEPIPEKSPQNGESGKEMDDD-KDANKSEISLVFEIALKR 219

  Fly   108 EMPLPCIEVVQQSGTPSAPEFVACCSVASIVRYGKSDKKKDARQRAAIEMLALISSNSDNLRPDQ 172
            .||: ..||:::||.|....||...||......|:.:.||.:::|||..:|..:.    .|.|
Mouse   220 NMPV-SFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELK----KLPP-- 277

  Fly   173 MQVASTSKL------KVV-----DMEESME------ELEALRRKKFTTYWELKEAG 211
            :.|....||      |.:     |..:.|.      :::..|::|...|..|.|.|
Mouse   278 LPVVEKPKLFFKKRPKTIVKAGPDYGQGMNPISRLAQIQQARKEKEPDYILLSERG 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
r2d2	NP_609152.1	DSRM	6..68	CDD:214634	8/23 (35%)
		DSRM_SF	102..158	CDD:380679	18/55 (33%)
Stau2	NP_079579.2	DSRM_SF	3..70	CDD:444671
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	71..94
		DSRM_STAU2_rpt2	98..179	CDD:380711	8/22 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	178..203		4/25 (16%)
		DSRM_STAU2_rpt3	206..272	CDD:380713	19/66 (29%)
		Nuclear localization signal 1	273..291		5/23 (22%)
		DSRM_STAU2_rpt4	304..389	CDD:380715	7/30 (23%)
		Nuclear localization signal 2. /evidence=ECO:0000250	373..412
		Required for dendritic transport. /evidence=ECO:0000250	381..570
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..413
		Staufen_C	465..523	CDD:465131
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	545..570