DRSC/TRiP Functional Genomics Resources

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Protein Alignment r2d2 and STAU2

DIOPT Version :9

Sequence 1:NP_001162903.1 Gene:r2d2 / 34066 FlyBaseID:FBgn0031951 Length:311 Species:Drosophila melanogaster
Sequence 2:NP_001157852.1 Gene:STAU2 / 27067 HGNCID:11371 Length:570 Species:Homo sapiens


Alignment Length:317 Identity:71/317 - (22%)
Similarity:121/317 - (38%) Gaps:56/317 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 NKSAVSALQEFCARTQINLPTYSFIPGEDG-----GYVCKVELLEIEALGNGRSKRDAKHLAASN 62
            |||.:|.:.|...:.  |:|....:..|.|     .:|.:|.:.|..|.|.|.||:.:|..||:.
Human   205 NKSEISLVFEIALKR--NMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATT 267

  Fly    63 ILRKIQLLPGIHGLMK--------DSTVGDLDEELTNLNRDMVKELRDYCVRREMPLPCIEVVQQ 119
            :|::::.||.:..:.|        ..|:.....|. ....:.:..|......::...|...::.:
Human   268 VLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEY-GQGMNPISRLAQIQQAKKEKEPDYVLLSE 331

  Fly   120 SGTPSAPEFVACCSVASIVRYGKSDKKKDARQRAAIEMLALISSNSDNLRPDQMQVASTSK---- 180
            .|.|...|||....|.:.|..|....||.|::.||..||..:...:.....||::....:|    
Human   332 RGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKASTNLQDQLEKTGENKGWSG 396

  Fly   181 -------------LKVVDMEESM-EELEALRRKKF--TT--YWELKEAGSVDHTGMRLCDRHNYF 227
                         ..::.:...: :|:||.|.|..  ||  |...|:......:          |
Human   397 PKPGFPEPTNNTPKGILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSS----------F 451

  Fly   228 KNFYPTLKKEAIEA----INSDEYESSKDKAMDVMSSLKITPKISEVESSSLVPLLS 280
            .:..||....|..|    :|.   .||..:|:.:..| ..||..|.|:.|..:..|:
Human   452 FSISPTSNSSATIARELLMNG---TSSTAEAIGLKGS-SPTPPCSPVQPSKQLEYLA 504

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
r2d2NP_001162903.1 DSRM 6..67 CDD:238007 18/65 (28%)
DSRM 95..158 CDD:238007 15/62 (24%)
STAU2NP_001157852.1 DSRM 9..70 CDD:214634
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..94
DSRM 96..180 CDD:214634
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 181..203
DSRM 209..273 CDD:214634 18/65 (28%)
Nuclear localization signal 1. /evidence=ECO:0000250 273..291 3/17 (18%)
DSRM 308..374 CDD:214634 17/65 (26%)
Nuclear localization signal 2. /evidence=ECO:0000250 373..412 3/38 (8%)
Required for dendritic transport. /evidence=ECO:0000250 381..570 28/138 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 387..409 1/21 (5%)
Staufen_C 459..523 CDD:318642 13/50 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 528..570
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3732
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S6775
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.760

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