DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment r2d2 and Prkra

DIOPT Version :9

Sequence 1:	NP_001162903.1	Gene:	r2d2 / 34066	FlyBaseID:	FBgn0031951	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_030106794.1	Gene:	Prkra / 23992	MGIID:	1344375	Length:	365	Species:	Mus musculus

Alignment Length:	182	Identity:	46/182 - (25%)
Similarity:	80/182 - (43%)	Gaps:	30/182 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KSAVSALQEF-----------CART--QINLPTYSFIPGEDGGYVCKVELLEIEALGNGRSKRDA 55
            |:.:..|.|:           |.|:  |:::||::|          :|.:.:|...|.|.||:.|
Mouse   114 KTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTF----------RVTVGDITCTGEGTSKKLA 168

  Fly    56 KHLAASNILRKIQLLPGIHGLMKDSTVGDLDEELTN-LNRDMVKELRDYCVRREMPLPCIEVVQQ 119
            ||.||...:..::....|...:.|..:.|..::..| ||  .:..|::..:.....||...:.|:
Mouse   169 KHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLN--PIGSLQELAIHHGWRLPEYTLSQE 231

  Fly   120 SGTPSAPEFVACCSVASIVRYGKSDKKKDARQRAAIEMLALISSNSDNLRPD 171
            .|.....|:...|.:.|.:..||...||.|::.||.:.||..|    |:.|:
Mouse   232 GGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFS----NISPE 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
r2d2	NP_001162903.1	DSRM	6..67	CDD:238007	19/73 (26%)
r2d2	NP_001162903.1	DSRM	95..158	CDD:238007	15/62 (24%)
Prkra	XP_030106794.1	DSRM_PRKRA_rpt1	113..183	CDD:380718	20/78 (26%)
		DSRM_PRKRA_rpt2	207..273	CDD:380720	18/67 (27%)
		DSRM_SF	320..>350	CDD:381777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46205
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910