Protein Alignment r2d2 and Tarbp2

DIOPT Version :9

• Sequence 1: NP_001162903.1
• Gene: r2d2 / 34066
• FlyBaseID: FBgn0031951
• Length: 311
• Species: Drosophila melanogaster
• Sequence 2: NP_033345.2
• Gene: Tarbp2 / 21357
• MGIID: 103027
• Length: 365
• Species: Mus musculus
• Alignment Length: 374
• Identity: 82/374 - (21%)
• Similarity: 124/374 - (33%)
• Gaps: 109/374 - (29%)

  Fly     4 KSAVSALQEFCARTQINLPTYSFIPGE----DGGYVCKVELLEIEALGNGRSKRDAKHLAASNIL 64
            |:.:|.|||:..|.. ..|.|..:..|    ...:..:|.:.:....|.|.||:.|||.||...|
Mouse    29 KTPISLLQEYGTRIG-KTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVAL 92

  Fly    65 RKIQ----LLPGIHGLMKDSTVGDLDEELTN--------------LNR----------------- 94
            :.::    |.|.:......|.:.....|.|.              |.|
Mouse    93 KHLKGGSMLEPALEDSSSFSLLDSSPPEDTPVVAAEAAAPVPSAVLTRSPPMEMQPPVSPQQSEC 157

  Fly    95 DMVKELRDYCVRREMPLPCIEVVQQSGTPSAPEFVACCSVASIVRYGKSDKKKDARQRAAIEML- 158
            :.|..|::..|::...||...|.|:||.....||...|.|...:..|....||.|::.||.:||
Mouse   158 NPVGALQELVVQKGWRLPEYMVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLL 222

  Fly   159 -----ALISSNSDNLRP--DQMQVASTSKLKVVDMEESMEELEALRRKKFTTYWE-LKEA----- 210
                 .|.:.:.:...|  |...:..:|:            |:.||.:.....|: |:.:
Mouse   223 RVHTVPLDARDGNEAEPDDDHFSIGVSSR------------LDGLRNRGPGCTWDSLRNSVGEKI 275

  Fly   211 --------GSVDHTGMRLCDRHNYFKNFYPTLKKEAIEAINSDEYESSKDKAMDVMSSLKITPKI 267
                    ||:...|...|                      |...|.|:::|..| |.|    .|
Mouse   276 LSLRSCSVGSLGALGSACC----------------------SVLSELSEEQAFHV-SYL----DI 313

  Fly   268 SEVESSSLVPLLSVELNCAFDVVLMAKET-------DIYDHIIDYFRTM 309
            .|:..|.|...| |||:.....|.....|       |.....:.|.|.|
Mouse   314 EELSLSGLCQCL-VELSTQPATVCYGSATTREAARGDAAHRALQYLRIM 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
r2d2	NP_001162903.1	DSRM	6..67	CDD:238007	19/64 (30%)
		DSRM	95..158	CDD:238007	19/62 (31%)
Tarbp2	NP_033345.2	Sufficient for interaction with PRKRA. /evidence=ECO:0000255|HAMAP-Rule:MF_03034	22..105		22/76 (29%)
		DSRM_TARBP2_rpt1	27..98	CDD:380719	20/69 (29%)
		Sufficient for interaction with PRKRA. /evidence=ECO:0000255|HAMAP-Rule:MF_03034	151..233		22/81 (27%)
		DSRM_TARBP2_rpt2	158..224	CDD:380681	21/65 (32%)
		Sufficient for interaction with DICER1. /evidence=ECO:0000255|HAMAP-Rule:MF_03034	227..365		34/175 (19%)
		Sufficient for interaction with PRKRA. /evidence=ECO:0000255|HAMAP-Rule:MF_03034	286..365		23/104 (22%)
		DSRM_TARBP2_rpt3	291..362	CDD:380722	22/99 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3732
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1093169at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46205
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920