DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment r2d2 and prkra

DIOPT Version :9

Sequence 1:	NP_001162903.1	Gene:	r2d2 / 34066	FlyBaseID:	FBgn0031951	Length:	311	Species:	Drosophila melanogaster
Sequence 2:	XP_004917795.2	Gene:	prkra / 100379994	XenbaseID:	XB-GENE-940706	Length:	312	Species:	Xenopus tropicalis

Alignment Length:	260	Identity:	63/260 - (24%)
Similarity:	107/260 - (41%)	Gaps:	46/260 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KSAVSALQEFCARTQINLPTYSFIPGE----DGGYVCKVELLEIEALGNGRSKRDAKHLAASNIL 64
            |:.:..|.||..:|. |.|.|:.|..|    :..:..::.:.:|.:.|.|.||:.||..||.:.|
Frog    30 KTPIQQLHEFGTKTG-NPPVYTLIKAEGEVHNPSFTFRLVIGDIVSSGEGPSKKAAKQKAAESAL 93

  Fly    65 RKIQLLPGIHG--LMKDSTVGDLDEE-LTNLNRDMVKELRDYCVRREMPLPCIEVVQQSGTPSAP 126
               .:|.|..|  |...:||.|:.:: |..:..:.|..|::..|::...||...|.|:||.|...
Frog    94 ---NILQGSTGKCLPVKNTVRDVPKQPLNQMKENPVGSLQELSVQKGWRLPEYTVAQESGPPHER 155

  Fly   127 EFVACCSVASIVRYGKSDKKKDARQRAAIEMLALISSNSDNLRPDQMQVASTSKLKVVDMEESME 191
            ||...|.|.:.|..|....||.|::.||.::|                    :|||.:.::....
Frog   156 EFTITCRVETFVETGSGTSKKVAKRVAADKLL--------------------TKLKAIPVDNMNI 200

  Fly   192 ELEALRRKKFTTYWELKEAGSVDHTGMRLCDRHNYFKNFYPTLKKEAIEAINSDEYESSKDKAMD 256
            .|..:.....:..|:.....|    |.::|           .||:..:....:|..:...|.|.:
Frog   201 SLNKVIGNNLSCTWDSMRNSS----GEKIC-----------MLKRSPLSIPYTDYVKMLNDLAKE 250

Fly 257 256
Frog 251 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
r2d2	NP_001162903.1	DSRM	6..67	CDD:238007	19/64 (30%)
r2d2	NP_001162903.1	DSRM	95..158	CDD:238007	21/62 (34%)
prkra	XP_004917795.2	DSRM_SF	29..98	CDD:412133	21/71 (30%)
		DSRM_PRKRA_rpt2	124..190	CDD:380720	22/85 (26%)
		DSRM_PRKRA_rpt3	238..309	CDD:380721	3/13 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1093169at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46205
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020