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Protein Alignment LKRSDH and Aass

DIOPT Version :9

Sequence 1:	NP_001285719.1	Gene:	LKRSDH / 34064	FlyBaseID:	FBgn0286198	Length:	928	Species:	Drosophila melanogaster
Sequence 2:	NP_038958.2	Gene:	Aass / 30956	MGIID:	1353573	Length:	926	Species:	Mus musculus

Alignment Length:	921	Identity:	470/921 - (51%)
Similarity:	663/921 - (71%)	Gaps:	17/921 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RVIQLRATIAHPFTRQRHSRVIAIRREDQSVWERRAPFGPTHVQKLVKQNVKVIVQPSNRRAYPM 67
            |:.:|||.::...   .|..|:|:||||.:.||||||..|.|::.:.|...||::|||||||...
Mouse     8 RLARLRACLSRGL---HHKPVMALRREDVNAWERRAPLAPKHIKGITKLGYKVLIQPSNRRAIHD 69

  Fly    68 QAYMQAGAHIQEDISDASVIFGVKQVPIDALIPGKTYCFFSHTIKAQESNMPLLDAILEKKIRLI 132
            :.|::||..:||||::|.:|.|||:.|.:.|:..|||.||||||||||:||.|||.:|:::||||
Mouse    70 KEYVRAGGILQEDITEACLILGVKRPPEEKLMSKKTYAFFSHTIKAQEANMNLLDEVLKQEIRLI 134

  Fly   133 DYERIIDERGARQVAFGKYAGVAGMVNILHGIGLRLLALGHHTPFMHIGPAHNYRNSSMARQAIR 197
            |||:::|.||:|.||||::||||||:|||||:|||||||||||||||:|.||||||||.|.||:|
Mouse   135 DYEKMVDHRGSRIVAFGQWAGVAGMINILHGMGLRLLALGHHTPFMHLGMAHNYRNSSQAVQAVR 199

  Fly   198 DCGYEISLGMMPKSIGPLTFVFTGSGNVSQGAQEVFSELPIEYVPPEMLRKVAEHGNQNKLYGCE 262
            |.|||||||:||||||||||||||:||||:||||||:|||.|||.|..||:|::.|:..|:||..
Mouse   200 DAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQEVFNELPCEYVEPHELREVSKTGDLRKVYGTV 264

  Fly   263 VSRSDHLERREGGGFDAKEYDEFPERYISTFSTKIAPYASVIVNGIYWAVGSPKLISIPDAKNLL 327
            :||..||.|:..|.:|..||:::||||.|.|:|.||||.:.::|||||...:|:|::..||::||
Mouse   265 LSRHHHLVRKTDGVYDPVEYEKYPERYTSRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLL 329

  Fly   328 RPANTPWLPTSKGSPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDTKSFKGP 392
            .|..:..:|. :|.|.|||:::||||||||.||||:||.|||||:.|||:||||:.....|.:|.
Mouse   330 VPVKSSVVPV-EGCPELPHKLVAICDISADTGGSIDFMTECTTIERPFCMYDADQQIIHDSVEGS 393

  Fly   393 GVLVCSIDNMPTQLPRESTDLFGELLAPHVHDIIKSDAKKPLAEENFSYPIQSAIIASNGQLTEG 457
            |:|:|||||:|.|||.|:|:.||::|.|:|.:::.|||.:||..:|||..::.|:|.|||.||:.
Mouse   394 GILMCSIDNLPAQLPIEATEYFGDMLYPYVEEMLLSDASQPLESQNFSPVVRDAVITSNGLLTDK 458

  Fly   458 FQYIQELRESQSHRSRHKMEG-SSESDKKVLVLGAGMVSAPLVEWLHREKDVSITVCSQVKEEAD 521
            ::|||:|||     ||.:::. |..:.|||||||:|.||.|::|:|.|:.::.||:.|.:..:..
Mouse   459 YKYIQKLRE-----SRERIQFLSMSTKKKVLVLGSGYVSGPVLEYLSRDNNIEITLGSDMTNQMQ 518

  Fly   522 RLAQQYAGVDSVYLDVNESTGHLQELCGRADVVVSLLPYSLHGMVARYCVAEGTHMVTASYLNDE 586
            :|:::| .::.|.|.|.:....||.|....|:|:|||||.||.:||:.|:....:||||||:...
Mouse   519 QLSKKY-NINPVSLTVGKQEAKLQSLVESQDLVISLLPYVLHPVVAKACIESRVNMVTASYITPA 582

  Fly   587 ISGLHEEAKAKGVTIMNEVGLDPGIDHLLALECIHEVQDKGAVVESFVSYCGGLPAPEHSNNALR 651
            :..|.:.....|:|::.|:|||||:||:||:|.|...::.||.|||:|||||||||||||:|.||
Mouse   583 MKELEKSVDDAGITVIGELGLDPGLDHMLAMETIDTAKELGATVESYVSYCGGLPAPEHSDNPLR 647

  Fly   652 YKFSWSPRGVLLNTLSAAKYLSQGQIVEISGGGELMSSPRSLDFLPGFALEGFPNRDSTKYGNLY 716
            |||||||.|||:|.:..|.||..|::|.::||...::|...:|:.||..|||:|||||.||..:|
Mouse   648 YKFSWSPVGVLMNIMQPASYLLNGKVVNVTGGVSFLNSVTPMDYFPGLNLEGYPNRDSIKYAEIY 712

  Fly   717 GLGRDVHTLLRGTIRYKGFSESIKPMQLLGLIDPEPHALLHPSGPDVTWRQLVIHLMGMSDSTIF 781
            |:. ..|||||||:||||:|:::.....||||:.|.:..|.|....:||:||:..|:|:|.|:.
Mouse   713 GIS-SAHTLLRGTLRYKGYSKALNGFVKLGLINREAYPALRPEANPLTWKQLLCDLVGISRSSP- 775

  Fly   782 YENLKQKLTERIG----DVDGIESLGLLDDTPVVKLNTPLDTLSHYLSKRLAFERDERDLVVLRH 842
            .|.||:.:..::|    .::..|.||||.|..|.:..:.:|..|.:|..:|::..:|:|::|:|.
Mouse   776 CEKLKEVVFTKLGGDNTQLEAAEWLGLLGDEQVPQAESIVDAFSKHLVSKLSYGPEEKDMIVMRD 840

  Fly   843 EVGIRWPDGRREERGINFVVYGQPQGHSAMAMTVGKPAAIAAKMILDGEIQERGVLLPFTPDIYR 907
            ..|||.|.|..|.:.|:.||||...|.||||.|||.|.|:||||:|||||:.:|::.|||.:||.
Mouse   841 SFGIRHPSGHLENKTIDLVVYGDFNGFSAMAKTVGLPTAMAAKMLLDGEIEAKGLMGPFTKEIYG 905

  Fly   908 PMLQRLRSEGL 918
            |:|:|:::||:
Mouse   906 PILERIKAEGI 916

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.