Protein Alignment LKRSDH and LKRSDH

DIOPT Version :10

• Sequence 1: NP_609150.2
• Gene: LKRSDH / 34064
• FlyBaseID: FBgn0286198
• Length: 928
• Species: Drosophila melanogaster
• Sequence 2: XP_314728.4
• Gene: LKRSDH / 1275481
• VectorBaseID: AGAMI1_004705
• Length: 930
• Species: Anopheles gambiae
• Alignment Length: 932
• Identity: 722/932 - (77%)
• Similarity: 827/932 - (88%)
• Gaps: 7/932 - (0%)

  Fly     1 MWRVIQLRATI-AHPFTRQRHS-RVIAIRREDQSVWERRAPFGPTHVQKLVKQNVKVIVQPSNRR 63
            |:|:::....: |..|||.:|: :|||:||||||||||||.|.|.:|:||:||.|||||||||||
Mosquito     1 MFRILKCSEHLSARHFTRGKHTGKVIALRREDQSVWERRASFSPANVKKLIKQGVKVIVQPSNRR 65

  Fly    64 AYPMQAYMQAGAHIQEDISDASVIFGVKQVPIDALIPGKTYCFFSHTIKAQESNMPLLDAILEKK 128
            |||||||:.|||.:|||||:|||||||||||:|||||.||||||||||||||||||||||.|||.
Mosquito    66 AYPMQAYLNAGATVQEDISEASVIFGVKQVPVDALIPQKTYCFFSHTIKAQESNMPLLDACLEKN 130

  Fly   129 IRLIDYERIIDERGARQVAFGKYAGVAGMVNILHGIGLRLLALGHHTPFMHIGPAHNYRNSSMAR 193
            |||||||:::|..|.|.||||||||||||||||||:|||||||||||||||:|||||||||||||
Mosquito   131 IRLIDYEKLMDRNGQRLVAFGKYAGVAGMVNILHGLGLRLLALGHHTPFMHVGPAHNYRNSSMAR 195

  Fly   194 QAIRDCGYEISLGMMPKSIGPLTFVFTGSGNVSQGAQEVFSELPIEYVPPEMLRKVAEHGNQNKL 258
            ||:|||||||||||||||||||||:|||||||||||||||.|||:|:|||||||||||||:.|||
Mosquito   196 QAVRDCGYEISLGMMPKSIGPLTFIFTGSGNVSQGAQEVFQELPVEFVPPEMLRKVAEHGSTNKL 260

  Fly   259 YGCEVSRSDHLERREGGGFDAKEYDEFPERYISTFSTKIAPYASVIVNGIYWAVGSPKLISIPDA 323
            |||||||||||||||||.||..|||::||:|:||||..|||||||||||||||||:||||:||||
Mosquito   261 YGCEVSRSDHLERREGGKFDPVEYDQYPEQYVSTFSKNIAPYASVIVNGIYWAVGAPKLITIPDA 325

  Fly   324 KNLLRPANTPWLPTSKGSPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDTKS 388
            |||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||.||
Mosquito   326 KNLLRPANTPWLPTSRGSPALPHRMLAICDISADPGGSIEFMNECTTIDTPFCLYDADRNKDQKS 390

  Fly   389 FKGPGVLVCSIDNMPTQLPRESTDLFGELLAPHVHDIIKSDAKKPLAEENFSYPIQSAIIASNGQ 453
            |||||||||||||||||||||:||.||:||.|:..||::|||.:||.|.||..|::.|||.|||.
Mosquito   391 FKGPGVLVCSIDNMPTQLPREATDFFGDLLYPYALDILQSDASRPLEEHNFCQPVEGAIICSNGN 455

  Fly   454 LTEGFQYIQELRESQSHRSRHKMEGSSESDKKVLVLGAGMVSAPLVEWLHREKDVSITVCSQVKE 518
            ||.||:||.|||| .::|||||.|||.|..|:|||||||.|||||||:||||.:|||.|.||.||
Mosquito   456 LTPGFEYINELRE-MNNRSRHKTEGSYEGKKRVLVLGAGFVSAPLVEYLHRESNVSIKVASQYKE 519

  Fly   519 EADRLAQQYAGVDSVYLDVNESTGHLQELCGRADVVVSLLPYSLHGMVARYCVAEGTHMVTASYL 583
            ||||||.:|.||:|||::|.:.:.:||.||..:||||||||||||.::|::|:|..||:|||||:
Mosquito   520 EADRLAHRYQGVESVYVNVQDESANLQNLCEESDVVVSLLPYSLHSVIAKHCIAGKTHLVTASYV 584

  Fly   584 NDEISGLHEEAKAKGVTIMNEVGLDPGIDHLLALECIHEVQDKGAVVESFVSYCGGLPAPEHSNN 648
            ||:||.||..|:..|||||||||||||||||||||||.:||:.|.|||||||:||||||||||||
Mosquito   585 NDDISALHSAAQDAGVTIMNEVGLDPGIDHLLALECIKDVQENGGVVESFVSFCGGLPAPEHSNN 649

  Fly   649 ALRYKFSWSPRGVLLNTLSAAKYLSQGQIVEISGGGELMSSPRSLDFLPGFALEGFPNRDSTKYG 713
            .||||||||||||||||||||||||:||:|||||||||||:||.|:||||||||||||||||||.
Mosquito   650 PLRYKFSWSPRGVLLNTLSAAKYLSKGQVVEISGGGELMSAPRELEFLPGFALEGFPNRDSTKYQ 714

  Fly   714 NLYGLGRDVHTLLRGTIRYKGFSESIKPMQLLGLIDPEPHALLHPSGPDVTWRQLVIHLMGMSDS 778
            :|||| .:::|||||||||||||::||||||||||||.||.||||.||::||||||::::|::|:
Mosquito   715 SLYGL-TNINTLLRGTIRYKGFSDTIKPMQLLGLIDPNPHPLLHPHGPELTWRQLVVNMLGLADA 778

  Fly   779 TIFYENLKQKLTERIGDVDGIESLGLLDDTPVVKLNTPLDTLSHYLSKRLAFERDERDLVVLRHE 843
            .||.||||.:|.||:|.::|:|.|||||:.||||:.:||||||:||||:||||..||||::|||:
Mosquito   779 DIFIENLKHRLAERVGTIEGLEELGLLDNVPVVKMGSPLDTLSYYLSKKLAFEDTERDLIILRHD 843

  Fly   844 VGIRWPDGRREERGINFVVYGQPQ---GHSAMAMTVGKPAAIAAKMILDGEIQERGVLLPFTPDI 905
            |||||.|||||||||||||||||.   ||||||.|||.|||||||||:|||||:|||:|||:.||
Mosquito   844 VGIRWSDGRREERGINFVVYGQPASTGGHSAMAKTVGFPAAIAAKMIIDGEIQQRGVVLPFSADI 908

  Fly   906 YRPMLQRLRSEGLTATETSRWL 927
            |||||.||..||||||.|::.|
Mosquito   909 YRPMLARLEQEGLTATTTTKVL 930

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LKRSDH	NP_609150.2	PLN02819	23..922	CDD:215439	712/901 (79%)
		LKR_SDH_like	23..465	CDD:240665	372/441 (84%)
LKRSDH	XP_314728.4	None