DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7149 and SELENOI

DIOPT Version :9

Sequence 1:	NP_001285718.1	Gene:	CG7149 / 34063	FlyBaseID:	FBgn0031948	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_277040.1	Gene:	SELENOI / 85465	HGNCID:	29361	Length:	397	Species:	Homo sapiens

Alignment Length:	396	Identity:	170/396 - (42%)
Similarity:	240/396 - (60%)	Gaps:	15/396 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCMRYLSEAHLRGFERYKYSSIDTSFLSVYVMHPFWNYCVKFVPKWLAPNVLTFVGFLMTVVNF 65
            |....|:|...|.||::||||::||:.||:||||||||..||..|.|||||::||.|||:.|.||
Human     1 MAGYEYVSPEQLAGFDKYKYSAVDTNPLSLYVMHPFWNTIVKVFPTWLAPNLITFSGFLLVVFNF 65

  Fly    66 ILIAYYDWGFEAANSETGNT-VPAWVWTVAAINILIYYNLDGMDGKQARRTGTSGPLGELFDHGL 129
            :|:||:|..|.|  |..|:. ||.|||.|..|...:.|.|||:||||||||.:|.||||||||||
Human    66 LLMAYFDPDFYA--SAPGHKHVPDWVWIVVGILNFVAYTLDGVDGKQARRTNSSTPLGELFDHGL 128

  Fly   130 DSYSAALIPIYLFSLF--GTHDLPPIRMFFVIWNVFLNFYLTHVEKYNTGVMFLPWGYDFTMWGV 192
            ||:|.....:.::|:|  |:..:....::.::|.|..:|.|:|.||||||::|||||||.:...:
Human   129 DSWSCVYFVVTVYSIFGRGSTGVSVFVLYLLLWVVLFSFILSHWEKYNTGILFLPWGYDISQVTI 193

  Fly   193 SGMLFVATVFGPE-MYRFSIYGFTMANMFEFVLIGSGMVSSHPIIARNIYLSYKNKTGKMRPMWE 256
            |.:..|..|.|.| .|...::.|...::|..::||..:..:.|:...|.:.||||.|.|:..::|
Human   194 SFVYIVTAVVGVEAWYEPFLFNFLYRDLFTAMIIGCALCVTLPMSLLNFFRSYKNNTLKLNSVYE 258

  Fly   257 MLRPFFAFVWLFVITVVWSFFSRNDVINKEPRILWILYGTIFSNIACRLIVAQMSDTRCDAFNVL 321
            .:.|.|:...||:::..|..:|.:|::...||:.:.:.||.|:|..|:|||.|||.|||...|.|
Human   259 AMVPLFSPCLLFILSTAWILWSPSDILELHPRVFYFMVGTAFANSTCQLIVCQMSSTRCPTLNWL 323

  Fly   322 MWPLAATVGVCCFPYYQQVFDSDLTSDTERWILYGLTIFSTLAHWHYGYGVVSEMCDHFHIRCFK 386
            :.||...|         .|.:..:.|..|..:||.||...||||.|||..||.::..||.|..|.
Human   324 LVPLFLVV---------LVVNLGVASYVESILLYTLTTAFTLAHIHYGVRVVKQLSSHFQIYPFS 379

  Fly   387 VRKSSS 392
            :||.:|
Human   380 LRKPNS 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7149	NP_001285718.1	CDP-OH_P_transf	4..389	CDD:294308	166/388 (43%)
SELENOI	NP_277040.1	CDP-OH_P_transf	6..382	CDD:294308	166/386 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146286
Domainoid	1	1.000	173	1.000	Domainoid score	I3697
eggNOG	1	0.900	-	-		E1_COG5050
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	331	1.000	Inparanoid score	I2440
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48063
OrthoDB	1	1.010	-	-		D465946at33208
OrthoFinder	1	1.000	-	-		FOG0002417
OrthoInspector	1	1.000	-	-		otm41284
orthoMCL	1	0.900	-	-		OOG6_106421
Panther	1	1.100	-	-	O	PTHR10414
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2123
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770