Protein Alignment Brd7-9 and Brd9

DIOPT Version :10

• Sequence 1: NP_609148.1
• Gene: Brd7-9 / 34062
• FlyBaseID: FBgn0031947
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001365876.1
• Gene: Brd9 / 105246
• MGIID: 2145317
• Length: 617
• Species: Mus musculus
• Alignment Length: 820
• Identity: 213/820 - (25%)
• Similarity: 340/820 - (41%)
• Gaps: 233/820 - (28%)

  Fly     1 MGSSKKHKKNKSERREKYEEYSQHQDPAQLQRGLKLILKVGSNATPEYSANSPMVDGGPPTAAEA 65
            ||  |||||:|:|.|..||:|:.    ..|::.|||:||||.:...|.|.:             .
Mouse     1 MG--KKHKKHKAEWRSSYEDYTD----TPLEKPLKLVLKVGGSEVTELSGS-------------G 46

  Fly    66 MMSPVPEELQDHQGHRERHKKSKKKKKKKDREKKHKHHKEKRHRSRDRHRDAGSDEDMMAGADDA 130
            ..|...::..||:  ||||::.|||||||..::||...:|:|.|..::.|....:.
Mouse    47 HDSSYYDDRSDHE--RERHREKKKKKKKKSEKEKHLDEEERRKRKEEKKRKREKEH--------- 100

  Fly   131 ACSGFAPSSVAPPAADPDSSQDGFSFMDDDQSQPLPENILFFAGITTDNSPSNCPVTKPIAPRKL 195
                          .|.:...|.|.                                    |.|.
Mouse   101 --------------CDSEGEADAFD------------------------------------PGKK 115

  Fly   196 DDILMGSSPNSSSLQSSSLGLIGSSPTKPLPDLLIPSPSTPGGANSLNALTPKALEAPKTPSSSS 260
            .::                        :|.||                    :.:.|.:|..:.:
Mouse   116 VEV------------------------EPPPD--------------------RPVRACRTQPAEN 136

  Fly   261 ESGREPRSCVLKLKQQKSPLNKLLEHLLRFLEKRDPHQFFAWPVTDDMAPGYSSIISRPMDFSTM 325
            ||               :|:.:||||.||.|:::|||.|||:||||.:|||||.||..||||.||
Mouse   137 ES---------------TPIQRLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTM 186

  Fly   326 RQKIDDHEYTALTEFTDDFKLMCENAIKYNHVDTVYNKAAKRLLQVGMKHLQPENLMRSLKPLSG 390
            :.||..:||.::|||..||||||:||:.||..||||.|.||::|..|.|.:..|.|: :||....
Mouse   187 KDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLL-ALKRSMS 250

  Fly   391 YMRELTARELGFELSSNDMSRENNDSADEGASTGAEEPR--------TPAQLEEEERKRTLRLEN 447
            :|:::                   |.:.:.|..|:|:|.        .|.|:|..::.:....|
Mouse   251 FMQDM-------------------DFSQQAALLGSEDPAAEEPVPEVVPVQVETTKKSKKPSRE- 295

  Fly   448 APKTHFEP-----YVDDLTGEE-ILAQVQNAAQQAKQRVNAKKNAHKMGFLRQMKDGTTTLNLVI 506
            .....|||     .:.|.|.|| :||.|::||.:|:.|:|......|||:|:::.||:...::|.
Mouse   296 VISCMFEPEGNACSLTDSTAEEHVLALVEHAADEARDRINRFLPGGKMGYLKKLGDGSLLYSVVN 360

  Fly   507 KEENEGPE---RVVTIGDLVGKLQKGSAQLQTRQVDKRNAVRTVKSLNYGAFASFAPTFDSRFST 568
            ..|.:..|   ..|.:..|..||..|...|..:. ::||.|..:.|    |..:.:...:|.|..
Mouse   361 APEPDADEEETHPVDLSSLSSKLLPGFTTLGFKD-ERRNKVTFLSS----ASTALSMQNNSVFGD 420

  Fly   569 LSAEETQLVLRTYGDASSAEYAESILQFTKDS-NYGTTIANGLLDILTNGEHSKSLDELYNMQLH 632
            |.::|.:|:...|||.:..:.|.|:.:|.||: :|...:.:.|||.:|.|:||:.:.:|  .|..
Mouse   421 LKSDEMELLYSAYGDETGVQCALSLQEFVKDAGSYSKKMVDDLLDQITGGDHSRMIFQL--KQRR 483

  Fly   633 SYEQREIEKCFEQEEETSSQQETTAQIEQEYEKYKNTHVDFKGLQSLGELGIDVSFLDGMEAEMK 697
            |...|..::               .::.....:.....:||..::...::.:|||.|..:....|
Mouse   484 SIPMRPADE---------------MKVGDPLGESGGPVLDFMSMKQYPDVSLDVSMLSSLGKVKK 533

  Fly   698 SYELNRRMHEHLSQNLTLIEKLRVAQHDRLSQPLPNHLGLVQPAGQEE---------IQTAQQLT 753
            ..: :...|.:|.:...|::.|..||.:|......::|..:..|.:.|         :...:|
Mouse   534 ELD-HEDSHLNLDETARLLQDLHEAQAERGGSRPSSNLSSLSTASEREHPPPGSPSRLSVGEQ-- 595

  Fly   754 QQISDLAKKLPPSAIADPYALRKAMGMSYAGLPPPRPVSP 793
                       |....|||..          |..|.|.:|
Mouse   596 -----------PDVAHDPYEF----------LQSPEPAAP 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brd7-9	NP_609148.1	Bromo_brd7_like	279..376	CDD:99945	58/96 (60%)
		DUF3512	452..632	CDD:463436	58/189 (31%)
Brd9	NP_001365876.1	Bromo_brd7_like	140..237	CDD:99945	58/96 (60%)
		DUF3512	306..485	CDD:463436	55/185 (30%)