Protein Alignment CG13796 and SLC6A5

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_004202.4
• Gene: SLC6A5 / 9152
• HGNCID: 11051
• Length: 797
• Species: Homo sapiens
• Alignment Length: 627
• Identity: 158/627 - (25%)
• Similarity: 256/627 - (40%)
• Gaps: 136/627 - (21%)

  Fly    81 DKCRGRWAKSADFYFASCTHA--------FSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLP 137
            :|.||.|:...||..:...:|        |..|.|.        :||. .|:|.|||.:....||
Human   188 NKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQ--------NGGG-AFLIPYLMMLALAGLP 243

  Fly   138 IFLIQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPW 202
            ||.::..||||:|.|.:|.::..|..:|.|.|:|::::....||::.....|.|...|...|:||
Human   244 IFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPW 308

  Fly   203 MSCNNSWNTQECSLHENYDVDDYRVDPHSTVEFFRSMIASTAKGSTSM----------------- 250
            .||||.|||.||.......:|...:..|..::...|....||..:.:|
Human   309 GSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTSQANKTFVSGSEE 373

  Fly   251 -----------------SISWSMLIGVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFL 298
                             .|.|.:.:.:...|::|.|.|.|.:...|||:         :|.|.|.
Human   374 YFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVV---------YFTATFP 429

  Fly   299 Y----LLIHEQVTFD----TLHYYWMPQLDSFD--SILATARTALLMAGGALGPGWGSIITLSSY 353
            |    :|:...||..    .:.|:..|:.:...  ::...|.|.:..   :|...||.:||||||
Human   430 YVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFF---SLSAAWGGLITLSSY 491

  Fly   354 NNFRRDAERLSIWV-CLTHITIGLMGLLCCNVAHDHFEDHVGMMPLHVDEKHHMQ--------FL 409
            |.|..:..|.::.| |....|....|.:..:|        :|.|.  .:.|.:::        ..
Human   492 NKFHNNCYRDTLIVTCTNSATSIFAGFVIFSV--------IGFMA--NERKVNIENVADQGPGIA 546

  Fly   410 YLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFDEF-ETLRSRRILVISSLV 473
            ::.:.....|...:| .||.:||.|:....|..:...:.:::|::.||| :.||:.:      .|
Human   547 FVVYPEALTRLPLSP-FWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHK------PV 604

  Fly   474 FCLTASSVYFCTQLGFSQLTQ--------LPNLAVFTHLLISGILVLM-TTWVYGRVRFQCDLQF 529
            |.|.....:|.  :||..:||        :...|....|:|..|..|: .::|||..||..|::.
Human   605 FTLGCCICFFI--MGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEM 667

  Fly   530 MLGKTISSFKIFFIRFATPIFLG--LC--LFQ---LTYLFTRDRIHDVLIYVSQGLI---LLTAI 584
            |:|...:.|......|.||..|.  ||  .:|   :||...|        |.:..::   |:.|.
Human   668 MIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYR--------YPNWSMVLGWLMLAC 724

  Fly   585 SYM------VYKVCRTNGDWRQRLQQCLAPH-DWHPVDADNR 619
            |.:      |.|:....|.:.:||:...:|. ||.|..|.:|
Human   725 SVIWIPIMFVIKMHLAPGRFIERLKLVCSPQPDWGPFLAQHR 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	141/566 (25%)
SLC6A5	NP_004202.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..118
		SLC6sbd_GlyT2	191..787	CDD:271389	157/624 (25%)