Protein Alignment CG13796 and Slc6a2

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_112633.2
• Gene: Slc6a2 / 83511
• RGDID: 621822
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 156/607 - (25%)
• Similarity: 259/607 - (42%)
• Gaps: 122/607 - (20%)

  Fly    84 RGRWAKSADFYFASCTHA--------FSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLPIFL 140
            |..|.|..||..:....|        |..|.:.        :||. .|:|.|.:.::...:|:|.
  Rat    56 RETWGKKIDFLLSVVGFAVDLANVWRFPYLCYK--------NGGG-AFLIPYTLFLIIAGMPLFY 111

  Fly   141 IQAFLGQFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSC 205
            ::..||||:..|..:.:::.|.|||:|||::|:.|....||::.....|.|...|....:||.:|
  Rat   112 MELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNC 176

  Fly   206 NNSWNTQECS---------LHENYDVDDYRVDPHSTVEFFRSMIASTAKGSTSMSI---SWSMLI 258
            .::||:..|:         |.::.....|:..|  ..||:...:....:.|....|   .|.:|:
  Rat   177 GHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTP--AAEFYERGVLHLHESSGIHDIGLPQWQLLL 239

  Fly   259 GVLSIWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYLLIHEQVTFD--------TLH--Y 313
            .::.:.:|:...|.|.|...|||:..:..|  .:||   |::|:...||..        .||  :
  Rat   240 CLMVVIVVLYFSLWKGVKTSGKVVWITATL--PYFV---LFVLLVHGVTLPGASNGINAYLHIDF 299

  Fly   314 YWMPQLDSFDSILATARTALLMAGGALGPGWGSIITLSSYNNF----RRDAERLSIWVCLTHITI 374
            |.:.:.    ::...|.|.:..   :||.|:|.:|..:|||.|    .|||...|...|:|....
  Rat   300 YRLKEA----TVWIDAATQIFF---SLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFIS 357

  Fly   375 G-----LMGLLCCNVAHDH---FED----HVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTPNLW 427
            |     ::|.:    ||:|   .||    ..|::.:...|         ..|.|.|     ...|
  Rat   358 GFAIFSILGYM----AHEHKVKIEDVATEGAGLVFVLYPE---------AISTLSG-----STFW 404

  Fly   428 AFLFFGMIFLSELCALIIQMMSVITALFDEFETLRSRRILVISSL--------VFCLTASSVYFC 484
            |.|||.|:....|.:.:..|.:|||.|.|:|:.|:..|.|...::        :||:|...:|.
  Rat   405 AVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYV- 468

  Fly   485 TQLGFSQLTQLPNLAVFTHLLISGILVLM----TTWVYGRVRFQCDLQFMLGKTISSFKIFFIRF 545
                   ||.|...|..|.:|.:   |||    .:|.||..||..|:|.|:|.....:.....:|
  Rat   469 -------LTLLDTFAAGTSILFA---VLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKF 523

  Fly   546 ATPIFLGLCLFQLTYLFTRDRIHDVLIY------VSQGLILLTAI---SYMVYKVCRTNGDWRQR 601
            .:|.|| |.:..::.:..:...:|..:|      |..|:.|.:.|   :|::||.....|...:|
  Rat   524 VSPAFL-LFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWER 587

  Fly   602 LQQCLAPHDWHPVDA--DNRRF 621
            :...:.|.:.|.:.|  |.|:|
  Rat   588 VAYGITPENEHHLVAQRDVRQF 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	141/545 (26%)
Slc6a2	NP_112633.2	SLC5-6-like_sbd	56..615	CDD:444915	156/607 (26%)