Protein Alignment CG13796 and slc6a3

DIOPT Version :9

• Sequence 1: NP_001137807.1
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_571830.1
• Gene: slc6a3 / 80787
• ZFINID: ZDB-GENE-010316-1
• Length: 629
• Species: Danio rerio
• Alignment Length: 642
• Identity: 163/642 - (25%)
• Similarity: 270/642 - (42%)
• Gaps: 111/642 - (17%)

  Fly    45 GGSLALAARRI--------RSRQVHSMAVRTGSAYD-TLERPYRHDKCRGR--WAKSADFYFASC 98
            |.|.|...|.:        ...|..|.::|...|:. |....:.|...:.|  |.|..||..:..
Zfish    26 GSSSAAGPREVELVLVKEQNGVQFTSSSLRNPGAHSHTHTHTHTHPSGQQRETWGKKIDFLLSVI 90

  Fly    99 THA--------FSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLPIFLIQAFLGQFSSSGTIS 155
            ..|        |..|.:.        :||. .|::.||:.|:...:|:|.::..|||::..|...
Zfish    91 GFAVDLANVWRFPYLCYK--------NGGG-AFLVPYLLFMVIAGMPLFYMELALGQYNREGAAG 146

  Fly   156 AFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSWNTQECSLHENY 220
            .:::.|||||:|:.::|::|...:||::.....|.|..:|....:||:.|||:||:..|| ..|.
Zfish   147 VWKICPIFKGVGFTVILISLYVGSYYNVIIAWALFYLFSSFSGELPWIHCNNTWNSPNCS-DPNA 210

  Fly   221 DV--DDYRVDPHSTVEFFRSMIASTAKGSTSMSIS---WSMLIGVLSIWLVVLAL-LLKPVAFIG 279
            .:  |.|:..|  .:|:|...:....:.|....:.   | .|...|::.:|||.. |.|.|...|
Zfish   211 TLLNDTYKTTP--ALEYFERGVLHVHESSGIDDLGAPRW-QLTACLAVVIVVLYFSLWKGVKTSG 272

  Fly   280 KVLRCSCVLMFGFFVAVFLYLLIHEQVT----FDTLH-YYWMPQLDSFDS-ILATARTALLMAGG 338
            ||:..:..:.:     |.|.:|:...||    .|.:. |..:..|..:|: :...|.|.:..
Zfish   273 KVVWITATMPY-----VVLTVLLLRGVTLPGAIDGIKAYLSVDFLRLYDAQVWIEAATQICF--- 329

  Fly   339 ALGPGWGSIITLSSYNNFRRDAERLSIWVCLTHITIGLMGLLCCNVAHDHFEDHVGMMPL-HVDE 402
            :||.|:|.:|..||||.|..:..|.:|      ||..:      |.....|...|....| ::.:
Zfish   330 SLGVGFGVLIAFSSYNKFSNNCYRDAI------ITSSI------NSLTSFFSGFVIFSFLGYMSQ 382

  Fly   403 KHHMQF-------LYLCFSYLFGRFTTTP--NLWAFLFFGMIFLSELCALIIQMMSVITALFDEF 458
            ||::..       ..|.|........|.|  ::||.:||.|:....:.:.:..|.||||.|.|||
Zfish   383 KHNVALDKVATDGPGLVFIIYPEAIATLPGSSVWAVIFFIMLLTLGIDSAMGGMESVITGLIDEF 447

  Fly   459 ETLRSRR-----ILVISSL---VFCLTASSVYFCTQLGFSQLTQLPNLAVFTHLLISGILV--LM 513
            :.|...|     .:|:|:.   :.|:|...:|.        .|.|.:.|..|.:|. |:|:  :.
Zfish   448 KFLHKHRELFTLFIVVSTFLISLICVTNGGIYV--------FTLLDHFAAGTSILF-GVLIEAIG 503

  Fly   514 TTWVYGRVRFQCDLQFMLGKTISSFKIFFIRFATPIFLGLCLFQLTYLFTRDRIHDVLIY----- 573
            ..|.||..||..|::.|:|:....:.....:|.:|.||   ||.:...|..........|
Zfish   504 IAWFYGVDRFSDDIEEMIGQRPGLYWRLCWKFVSPCFL---LFMVVVSFATFNPPKYGSYYFPTW 565

  Fly   574 -------VSQGLILLTAISYMVYKVCRTNGDWRQRLQQCLAPH-DWHPVD-ADNRRF 621
                   :|...:::..: |..||.|...|.:..:|...:.|. |.|.|: .:.|:|
Zfish   566 ATMVGWCLSISSMIMVPL-YAFYKFCSLPGSFCDKLAYAITPETDHHLVERGEVRQF 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	138/531 (26%)
slc6a3	NP_571830.1	SLC6sbd_DAT1	76..623	CDD:212083	153/592 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820