Protein Alignment CG13796 and Slc6a1

DIOPT Version :10

• Sequence 1: NP_609140.2
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_077347.1
• Gene: Slc6a1 / 79212
• RGDID: 620533
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 572
• Identity: 156/572 - (27%)
• Similarity: 249/572 - (43%)
• Gaps: 85/572 - (14%)

  Fly    84 RGRWAKSADFYFASCTHAFSSLIFSELSTFGILHG--GWLLFIIAYLMGMLFYSLPIFLIQAFLG 146
            |..|....||..:...:|..   ...:..|..|.|  |...|:|.|.:.::|..:|:||::..||
  Rat    44 RDTWKGRFDFLMSCVGYAIG---LGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLG 105

  Fly   147 QFSSSGTISAFRVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSWNT 211
            |::|.|.:..:::||:|||:|.|..:|:.....||.:.....:.|..||....:||..|:|.|||
  Rat   106 QYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNT 170

  Fly   212 QECSLHENYDVDDYRVDPHSTVEFF-RSMIASTAKGSTSMSISWSMLIGVLSIWLVVLALLLKPV 275
            ..|  ..||.:.:......:.|||: |:|...|........|.|.:.|.:...|::|...:.|.|
  Rat   171 DRC--FSNYSLVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWVLVYFCIWKGV 233

  Fly   276 AFIGKVLRCSCVLMFGFFVAVFLYLLIHEQVTF----DTLHYYWMPQLD--SFDSILATARTALL 334
            .:.|||:..|....:     :.|.:|....||.    :.:.:|..|...  |...:...|.|.:.
  Rat   234 GWTGKVVYFSATYPY-----IMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIF 293

  Fly   335 MAGGALGPGWGSIITLSSYNNFRRDAERLSIWV-CLTHITIGLMGLLCCNVAHDHFEDHVGMMPL 398
            .   :.|.|.||:|.|.|||:|..:..|.||.| |:...|....|.:..::        ||.| .
  Rat   294 F---SYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSI--------VGFM-A 346

  Fly   399 HVDEKHHMQ-------FLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMMSVITALFD 456
            ||.::....       ..:|.:.....:...:| |||.|||.|:.:..:.:....:...||||.|
  Rat   347 HVTKRSIADVAASGPGLAFLAYPEAVTQLPISP-LWAILFFSMLLMLGIDSQFCTVEGFITALVD 410

  Fly   457 EF-ETLRSRRILVISSLVFCLTASSVYFCTQLGFSQLTQ--LPNLAVFTHLLISGILVLM----- 513
            |: ..||:||.|.|:::  |:.:   |.   :|.|.:||  :....:|.:...||:.:|.
  Rat   411 EYPRLLRNRRELFIAAV--CIVS---YL---IGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFE 467

  Fly   514 ---TTWVYGRVRFQCDLQFMLGKTISSFKIFFIRFATPIFL-GLCLF---QLT------YLFTRD 565
               .:|.||..||..::|.|:|.....:......|.|||.: |:.||   |:|      |:|.:
  Rat   468 CVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFLFSAVQMTPLTMGSYVFPK- 531

  Fly   566 RIHDVLIYVSQGLILLTAIS-------YMVYKVCRTNGDWRQRLQQCLAPHD 610
                    ..||:..|.|:|       ||.|......|..:||||..:.|.:
  Rat   532 --------WGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSE 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_609140.2	SLC5-6-like_sbd	123..610	CDD:444915	147/529 (28%)
Slc6a1	NP_077347.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		SLC6sbd_GAT1	2..599	CDD:212075	156/572 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	577..599
		PDZ-binding	597..599