DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13796 and zgc:158427

DIOPT Version :9

Sequence 1:	NP_001137807.1	Gene:	CG13796 / 34051	FlyBaseID:	FBgn0031939	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	XP_017207457.1	Gene:	zgc:158427 / 790932	ZFINID:	ZDB-GENE-061215-110	Length:	579	Species:	Danio rerio

Alignment Length:	592	Identity:	147/592 - (24%)
Similarity:	248/592 - (41%)	Gaps:	105/592 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 RGRWAKSADFYFASCTHAFSSLIFSELSTFGIL---HGGWLLFIIAYLMGMLFYSLPIFLIQAFL 145
            ||.|.|..:|..|...:...   ...:..|..|   :||. :|:|.||:.::...:|:||::..:
Zfish    11 RGFWGKKTEFLLAVAGNVVG---LGNVWRFPYLCYRNGGG-VFLIPYLVFVVTCGVPLFLLETAM 71

  Fly   146 GQFSSSGTISAF-RVAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMSCNNSW 209
            |||:..|.|:.: |:.|:.:|||||..|..|.:..|::|.....|.|.::|....:||.||:|.|
Zfish    72 GQFTHEGGITCWHRLCPLAQGIGYAGQLTVLYSCMYFTIILAWALFYLISSFSSQLPWASCDNIW 136

  Fly   210 NTQEC------SLHENYDVDDYRVDPHSTVEFFRSMIASTAKGSTSM-SISWSMLIGVLSIWLVV 267
            ||..|      :|..|...........:..||:...:.|.:.|...: .|:|.:|:.::::|::.
Zfish   137 NTDNCVNLAAGNLTFNRTTQMLINSTSAATEFWERRVLSLSGGIEDIGKINWEILLCLIAMWIIC 201

  Fly   268 LALLLKPVAFIGKVLRCSCVLMFGFFVAVFLY-----LLIH--------EQVTFDTLHYYWMPQL 319
            ...:.|.|...|||:         :|.|.|.|     |||.        :.:.|   :.|..|..
Zfish   202 YFCIWKGVKSTGKVV---------YFTATFPYVMLIVLLIRGLTLPGALQGIVF---YLYPEPAR 254

  Fly   320 DSFDSILATARTALLMAGGALGPGWGSIITLSSYNNFRRDAERLSIWVCLTHI-TIGLMGLLCCN 383
            .:...:...|.|.:..:...:|   |.:|:|.|||.:..:..|...|:||.:. |..:.|....:
Zfish   255 LADPQVWMEAGTQIFFSYSVIG---GVLISLGSYNQYNNNCYRDCFWLCLLNSGTSFVAGFAVFS 316

  Fly   384 VAHDHFEDHVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTPNLWAFLFFGMIFLSELCALIIQMM 448
            |.  .|..||..:|:....:......::.:..... ....|.|||..||.||.|..|....:.:.
Zfish   317 VL--GFMAHVQGVPIEEVAESGPGLAFIAYPQAVA-MMPFPQLWAVCFFIMIILLGLDTQFVSVE 378

  Fly   449 SVITALFDEF-ETLR--SRRILVISSLVFCLTA--SSVYFCTQLGFSQLTQLPN----------L 498
            .|||::.|.| |.||  .||.|::  |:.|||.  ..:...|:.|........|          |
Zfish   379 CVITSVMDLFPEVLRRAGRRELLV--LLLCLTCFFGQLIMVTEGGMYVFQLFDNYACNGACLLFL 441

  Fly   499 AVFTHLLISGILVLMTTWVYGRVRF----------QCDLQFMLG-------KTISSFKIFFIRFA 546
            :||..|.|.        |::|..:.          :.:..|||.       .:::||....:|:
Zfish   442 SVFESLAIG--------WIFGAEKMFDIIEDMTESRPNYWFMLCWKYLTPLVSLTSFVYSMVRY- 497

  Fly   547 TPIFLGLCLFQLTYLFTRDRIHDVLIYVSQGLILLTAI----SYMVYKVCRTNGDWRQRLQQCLA 607
            ||:           .|.|..|:....||...|:.|::|    ::.:.::|...|..:||.:...:
Zfish   498 TPL-----------TFNRWYIYPDWAYVLGWLLALSSILLVPAWALGQMCAGKGSLKQRWRHLSS 551

  Fly   608 PHDWHPV 614
            |....|:
Zfish   552 PETNFPL 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	136/544 (25%)
zgc:158427	XP_017207457.1	SLC6sbd-TauT-like	11..552	CDD:271387	145/584 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920