Protein Alignment CG13796 and slc6a4b

DIOPT Version :9

• Sequence 1: NP_001137807.1
• Gene: CG13796 / 34051
• FlyBaseID: FBgn0031939
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001170930.1
• Gene: slc6a4b / 664770
• ZFINID: ZDB-GENE-060314-2
• Length: 591
• Species: Danio rerio
• Alignment Length: 581
• Identity: 160/581 - (27%)
• Similarity: 256/581 - (44%)
• Gaps: 101/581 - (17%)

  Fly    84 RGRWAKSADFYFASCTHA--------FSSLIFSELSTFGILHGGWLLFIIAYLMGMLFYSLPIFL 140
            |.:|:|..||..:....|        |..:.:.        :||. .|:|.|::..:|..:|:|.
Zfish    38 RDKWSKKMDFLLSVIGFAVDLGNVWRFPYICYQ--------NGGG-AFLIPYVLMAVFGGVPLFY 93

  Fly   141 IQAFLGQFSSSGTISAFR-VAPIFKGIGYAILLLNLGTLTYYSIAAVVPLIYTVNSIHPVIPWMS 204
            ::..||||..:|.||.:: :.|||||||:||.::.|....||:......|.|..:|....:||.|
Zfish    94 MELALGQFHRTGAISIWKHICPIFKGIGFAICIIALYVSFYYNTIIAWALFYFYSSFSSTLPWTS 158

  Fly   205 CNNSWNTQECSLH---ENYDVDDYRVDPHSTVEFF-RSMIA---STAKGSTSMSISWSMLIGVLS 262
            |:|.|||:.|:.:   :|....:|...|  ..||: |:::|   |:..|:... |.|.:::.:..
Zfish   159 CDNDWNTENCTNYFGKDNVTWTNYSRSP--AEEFYTRNVLAVHESSGLGNVGY-IRWQLMLCLFL 220

  Fly   263 IWLVVLALLLKPVAFIGKVLRCSCVLMFGFFVAVFLYLLIHEQV---TFDTLHYYWMPQLDSF-- 322
            |:.:|...|.|.|...|||:..:..|.:    .|.|.|:|....   .:..:.:|..|:.:..
Zfish   221 IFTIVYFSLWKGVKTSGKVVWVTATLPY----VVLLILMIRGATLPGAWKGVVFYLNPKWEKLKE 281

  Fly   323 DSILATARTALLMAGGALGPGWGSIITLSSYNNFR----RDAERLSIWVCLTHITIG-----LMG 378
            .|:...|...:..   :||||:|.::.|||||.|.    |||...|:..|||....|     ::|
Zfish   282 TSVWVDAAAQIFF---SLGPGFGVLLALSSYNPFTNNCYRDAIVTSLVNCLTSFVSGFVIFTVLG 343

  Fly   379 LLCCNVAHDHFEDHVGMMPLHVDEKHHMQFLYLCFSYLFGRFTTTP----NLWAFLFFGMIFLSE 439
            .:.       .:.:|.:..:..|:...:.|:            |.|    |:....||.:||...
Zfish   344 YMA-------EQRNVNVEDVARDKGPSLLFI------------TYPEAIANMVGSTFFAIIFFVM 389

  Fly   440 LCALIIQ-----MMSVITALFDEF-ETLRSRRILVISSLVFCLTASSVYFCTQLGFSQLTQLPNL 498
            :..|.:.     :.::|||:.||: :.|..||.|.:..||......|:...|:.|...:..|...
Zfish   390 MITLGLDSTFGGLEAIITAVMDEYPDVLSHRRELFVLGLVVVCFLGSLSTLTKGGAYVVKLLEEF 454

  Fly   499 AVFTHLLISGILVLMTT---WVYGRVRFQCDLQFMLGKTISSF-KIFFIRFATPIFLG------- 552
            .|.:.::  .|:.|..|   |.||..||..|::.|||.|...| |:.::.. :|.||.
Zfish   455 GVGSSII--AIVFLEATAVSWFYGINRFSNDIKSMLGYTPGLFWKVCWVAI-SPAFLAYIIISSL 516

  Fly   553 -----LCLFQLTYLFTRDRIHDVLIYVSQGLILLTAISYMVYKVCRTNGDWRQRLQQCLAP 608
                 |.||.  |.|....|....|..:...|.:..  |||||:..|.|..:|||..||.|
Zfish   517 LNPQTLTLFD--YEFPDWSITVGYIIGASSFIWIPI--YMVYKLVWTPGSLKQRLAVCLRP 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13796	NP_001137807.1	SLC5-6-like_sbd	123..610	CDD:294310	151/534 (28%)
slc6a4b	NP_001170930.1	SLC6sbd_SERT	38..574	CDD:271399	160/581 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820